Nigericin

221 Cited Publications
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Based on 221 publication(s) in Google Scholar

Nigericin is an antibiotic derived from Streptomyces hygroscopicus that act as a K+/H+ ionophore, promoting K+/H+ exchange across mitochondrial membranes. Nigericin is a NLRP3 activator. Nigericin shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt/β-catenin signals. Nigericin induces pyroptosis through caspase 1/GSDMD in TNBC.

For research use only. We do not sell to patients.

  • Purity: 99.64%
  • CAS No.: 28380-24-7
  • Formula: C40H68O11
  • Molecular Weight:724.96
  • Storage:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

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100 mg

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