1. Metabolic Enzyme/Protease
  2. Glutathione Peroxidase
  3. (1S,3R)-RSL3

(1S,3R)-RSL3 

Cat. No.: HY-100218A Purity: 99.87%
Handling Instructions

(1S,3R)-RSL3 is a glutathione peroxidase 4 (GPX4) inhibitor with an EC50 of 10 μM in cellular assay.

For research use only. We do not sell to patients.

(1S,3R)-RSL3 Chemical Structure

(1S,3R)-RSL3 Chemical Structure

CAS No. : 1219810-16-8

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 87 In-stock
Estimated Time of Arrival: December 31
2 mg USD 60 In-stock
Estimated Time of Arrival: December 31
5 mg USD 90 In-stock
Estimated Time of Arrival: December 31
10 mg USD 160 In-stock
Estimated Time of Arrival: December 31
25 mg USD 330 In-stock
Estimated Time of Arrival: December 31
50 mg USD 560 In-stock
Estimated Time of Arrival: December 31
100 mg USD 990 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 5 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

(1S,3R)-RSL3 is a glutathione peroxidase 4 (GPX4) inhibitor with an EC50 of 10 μM in cellular assay.

Molecular Weight

440.88

Formula

C₂₃H₂₁ClN₂O₅

CAS No.

1219810-16-8

SMILES

O=C([[email protected]]1CC2=C([[email protected]](C3=CC=C(C(OC)=O)C=C3)N1C(CCl)=O)NC4=C2C=CC=C4)OC

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (226.82 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2682 mL 11.3410 mL 22.6819 mL
5 mM 0.4536 mL 2.2682 mL 4.5364 mL
10 mM 0.2268 mL 1.1341 mL 2.2682 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (5.67 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.67 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
(1S,3R)-RSL3
Cat. No.:
HY-100218A
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