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  4. (1R,3S)-RSL3

(1R,3S)-RSL3 is the less active (1R,3S)-enantiomer of RSL3 ((1S,3R)-RSL3). (1R,3S)-RSL3 and RSL3 induce cell death in HT22 wild-type cells with EC50 values of 5.2 µM and 0.004 µM, rspectively.

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(1R,3S)-RSL3 Chemical Structure

(1R,3S)-RSL3 Chemical Structure

CAS No. : 1219810-13-5

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Other Forms of (1R,3S)-RSL3:

(1R,3S)-RSL3 Related Antibodies

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Description

(1R,3S)-RSL3 is the less active (1R,3S)-enantiomer of RSL3 ((1S,3R)-RSL3). (1R,3S)-RSL3 and RSL3 induce cell death in HT22 wild-type cells with EC50 values of 5.2 µM and 0.004 µM, rspectively[1].

In Vitro

(1R,3S)-RSL3 (0.1 nM-100 µM; 16 h) induces cell death in HT22 wild-type (WT) and HT22 Bid CRISPR KO cells with EC50 values of 5.2 µM and 28.8 µM, rspectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(1R,3S)-RSL3 Related Antibodies

Cell Viability Assay[1]

Cell Line: HT22 WT and HT22 Bid CRISPR KO cells
Concentration: 0.1 nM-100 µM
Incubation Time: 16 h
Result: Inhibited cells growth.
Molecular Weight

440.88

Formula

C23H21ClN2O5
CAS No.
SMILES

O=C([C@@H]1CC2=C([C@@H](C3=CC=C(C(OC)=O)C=C3)N1C(CCl)=O)NC4=C2C=CC=C4)OC
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(1R,3S)-RSL3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(1R,3S)-RSL31219810-13-5Others(1R,3S)-enantiomerInhibitorinhibitorinhibit

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