870087-37-9
Chemical Structure
Apilimod hydrochloride
Synonym(s): STA 5326 hydrochloride; LAM-002A free base hydrochloride; AIT-101 hydrochloride
- CAS No.: 870087-37-9
- Formula:C23H28Cl2N6O2
- Molecular Weight:491.41
InChIKey: PJPZEUCDSIGFOW-OKUPSQOASA-N
SMILES: CC1=CC=CC(/C=N/NC2=CC(N3CCOCC3)=NC(OCCC4=CC=CC=N4)=N2)=C1.Cl.Cl
Biological Activity: Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Apilimod hydrochloride | Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
