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Cat. No.: HY-175631

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PIKfyve ligand-1

PIKfyve ligand-1 is a PIKfyve ligand, which can be used for the synthesis of PROTACs, such as PIK5-12d (HY-155994).

For research use only. We do not sell to patients.

CAS No.: 3036457-23-2
Formula: C₂₉H₃₆N₆O₄
Molecular Weight:532.63

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

PIKfyve ligand-1 Chemical Structure

CAS No.: 3036457-23-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

PIKfyve ligand-1 is a PIKfyve ligand, which can be used for the synthesis of PROTACs, such as PIK5-12d (HY-155994)^[1].

Chemical Information

CAS No. 3036457-23-2
Molecular Weight 532.63
Formula C₂₉H₃₆N₆O₄
SMILES

CC1=CC=CC(/C=N/NC2=NC(OCCC3=CC=C(NC(OC(C)(C)C)=O)C=C3)=NC(N4CCOCC4)=C2)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Li C,et al. Discovery of a First-in-Class Degrader for the Lipid Kinase PIKfyve. J Med Chem. 2023 Sep 14;66(17):12432-12445. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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