1. Alkaloids
  2. Phellodendrine chloride

Phellodendrine chloride 

Cat. No.: HY-N0735 Purity: 98.97%
Handling Instructions

Phellodendrine chloride is a plant alkaloid found in Phellodendron amurense. Phellodendrine chloride suppresses the proliferation of KRAS mutated pancreatic cancer cells through inhibition of nutrients uptake via macropinocytosis .

For research use only. We do not sell to patients.

Phellodendrine chloride Chemical Structure

Phellodendrine chloride Chemical Structure

CAS No. : 104112-82-5

Size Price Stock Quantity
5 mg USD 80 In-stock
Estimated Time of Arrival: December 31
10 mg USD 140 In-stock
Estimated Time of Arrival: December 31
20 mg USD 230 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Phellodendrine chloride:

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Description

Phellodendrine chloride is a plant alkaloid found in Phellodendron amurense. Phellodendrine chloride suppresses the proliferation of KRAS mutated pancreatic cancer cells through inhibition of nutrients uptake via macropinocytosis [1].

Molecular Weight

377.86

Formula

C₂₀H₂₄ClNO₄

CAS No.

104112-82-5

SMILES

C[[email protected]@+]12CCC3=CC(OC)=C(O)C=C3[[email protected]]1([H])CC4=CC(O)=C(OC)C=C4C2.[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (132.32 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6465 mL 13.2324 mL 26.4648 mL
5 mM 0.5293 mL 2.6465 mL 5.2930 mL
10 mM 0.2646 mL 1.3232 mL 2.6465 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 5 mg/mL (13.23 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 5 mg/mL (13.23 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 5 mg/mL (13.23 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

PhellodendrineOthersmacropinocytosispancreaticcancerInhibitorinhibitorinhibit

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Product Name:
Phellodendrine chloride
Cat. No.:
HY-N0735
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