1. PI3K/Akt/mTOR
    NF-κB
  2. Akt
    NF-κB
  3. Phellodendrine

Phellodendrine 

Cat. No.: HY-N0427 Purity: 99.37%
Handling Instructions

Phellodendrine, a isoquinoline alkaloid, is one of important characteristic ingredients in the Phellodendri chinensis cortex. phellodendrine is against AAPH-induced oxidative stress through regulating the AKT/NF-κB pathway. Phellodendrine has good antioxidant, and anti-inflammatory effect .

For research use only. We do not sell to patients.

Phellodendrine Chemical Structure

Phellodendrine Chemical Structure

CAS No. : 6873-13-8

Size Price Stock Quantity
5 mg USD 99 In-stock
Estimated Time of Arrival: December 31
10 mg USD 168 In-stock
Estimated Time of Arrival: December 31
20 mg USD 286 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Phellodendrine, a isoquinoline alkaloid, is one of important characteristic ingredients in the Phellodendri chinensis cortex. phellodendrine is against AAPH-induced oxidative stress through regulating the AKT/NF-κB pathway. Phellodendrine has good antioxidant, and anti-inflammatory effect [1].

IC50 & Target[1]

Akt

 

NF-κB

 

Molecular Weight

342.41

Formula

C₂₀H₂₄NO₄

CAS No.

6873-13-8

SMILES

OC1=C(OC)C=C2CC[[email protected]@+]3(C)CC4=CC(OC)=C(O)C=C4C[[email protected]@]3([H])C2=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (14.60 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9205 mL 14.6024 mL 29.2048 mL
5 mM 0.5841 mL 2.9205 mL 5.8410 mL
10 mM 0.2920 mL 1.4602 mL 2.9205 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

PhellodendrineAktNF-κBPKBProtein kinase BNuclear factor-κBNuclear factor-kappaBInhibitorinhibitorinhibit

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Product Name:
Phellodendrine
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HY-N0427
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