1. Signaling Pathways
  2. PI3K/Akt/mTOR
  3. mTOR
  4. mTOR Inhibitors

mTOR Inhibitors

mTOR

mTORC1

mTORC2

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Sorry. There is currently no product that acts on isoform mTOR together.

Please try each isoform separately.

mTOR Specific Inhibitors, Activators & Modulators
Product Name mTOR mTORC1 mTORC2 mTOR Selectivity Purity
PKI-179 hydrochloride
mTOR, IC50: 0.42 nM
    Selective Inhibitor 98.11%
PKI-179
mTOR, IC50: 0.42 nM
    Selective Inhibitor ≥98.0%
mTOR inhibitor-2
mTOR, IC50: 7 nM
    Selective Inhibitor
RapaLink-1
mTOR
    Pan Inhibitor ≥98.0%
HDACs/mTOR Inhibitor 1
mTOR, IC50: 1.2 nM
    Pan Inhibitor 98.21%
PQR530
mTOR, Kd: 0.33 nM
    Pan Inhibitor 99.93%
hSMG-1 inhibitor 11j
mTOR, IC50: 50 nM
    Pan Inhibitor 99.81%
Arnicolide D
mTOR
    Pan Inhibitor ≥99.0%
PI3K/mTOR Inhibitor-2
mTOR, IC50: 4.7 nM
    Pan Inhibitor 99.45%
mTOR inhibitor-8
mTOR
    Pan Inhibitor 98.04%
Hederacolchiside A1
mTOR
    Pan Modulator ≥99.0%
Rotundic acid
mTOR
    Pan Inhibitor ≥99.0%
TML-6
mTOR
    Pan Inhibitor 98.34%
BGT226
mTOR
    Pan Inhibitor
RP-3500
mTOR, IC50: 120 nM
    Pan Inhibitor
PI3K/mTOR Inhibitor-1
mTOR, IC50: 186 nM
    Pan Inhibitor
PI3K/mTOR Inhibitor-3
mTOR
    Pan Inhibitor
8-Aminoadenosine
mTOR
    Pan Inhibitor
hSMG-1 inhibitor 11e
mTOR, IC50: 45 nM
    Pan Inhibitor 99.18%
Torin 1
mTOR, IC50: 3 nM
mTORC1, IC50: 2-10 nM
mTORC2, IC50: 2-10 nM
Inhibitor ≥98.0%
AZD-8055
mTOR, IC50: 0.8 nM
    Inhibitor ≥95.0%
Sapanisertib
mTOR, IC50: 1 nM
    Inhibitor ≥98.0%
Dactolisib
mTOR, IC50: 20.7 nM
    Inhibitor 99.94%
3BDO
mTOR
    Activator 99.91%
Salidroside
mTOR
    Activator ≥98.0%
Vistusertib
mTOR, IC50: 2.81 nM
    Inhibitor 98.53%
Torin 2
mTOR, IC50: 2.81 nM
mTOR, EC50: 0.25 nM (Cell Assay)
    Inhibitor 99.98%
Torkinib
mTOR, IC50: 8 nM
mTORC1, IC50: 30 nM
mTORC2, IC50: 58 nM
Inhibitor 98.76%
PF-04691502
mTOR, Ki: 16 nM
    Inhibitor 99.64%
Dactolisib Tosylate
mTOR, IC50: 20.7 nM
    Inhibitor 99.88%
Samotolisib
mTOR, IC50: 165 nM
    Inhibitor 99.42%
OSI-027
mTOR, IC50: 4 nM
mTORC1, IC50: 22 nM
mTORC2, IC50: 65 nM
Inhibitor ≥98.0%
PKI-402
mTOR, IC50: 3 nM
    Inhibitor 99.79%
Apitolisib
mTOR, Ki: 17 nM
    Inhibitor 98.26%
BGT226 maleate
mTOR
    Inhibitor 99.73%
CC-115
mTOR, IC50: 21 nM
    Inhibitor 98.04%
Voxtalisib
mTOR, IC50: 157 nM
mTORC1, IC50: 160 nM
mTORC2, IC50: 910 nM
Inhibitor 99.46%
Gedatolisib
mTOR, IC50: 1.6 nM
    Inhibitor ≥98.0%
Bimiralisib
mTOR, IC50: 89 nM
    Inhibitor 98.74%
GSK1059615
mTOR, IC50: 12 nM
    Inhibitor ≥99.0%
WYE-354
mTOR, IC50: 5 nM
    Inhibitor ≥98.0%
WYE-132
mTOR, IC50: 0.19 nM
    Inhibitor 99.40%
PP121
mTOR, IC50: 10 nM
    Inhibitor 99.08%
VS-5584
mTOR, IC50: 37 nM
    Inhibitor ≥95.0%
mTOR inhibitor-3
mTOR, Ki: 1.5 nM
    Inhibitor 99.08%
GDC-0349
mTOR, Ki: 3.8 nM
    Inhibitor ≥95.0%
ETP-46464
mTOR, IC50: 0.6 nM
    Inhibitor ≥95.0%
GNE-317
mTOR
    Inhibitor 99.31%
CZ415
mTOR, pIC50: 8.07
    Inhibitor 98.43%
Onatasertib
mTOR, IC50: 16 nM
    Inhibitor ≥97.0%
XL388
mTOR, IC50: 9.9 nM
    Inhibitor 99.25%
WAY-600
mTOR, IC50: 9 nM
    Inhibitor 95.12%
GNE-477
mTOR, Ki: 21 nM
    Inhibitor 98.70%
PF-04979064
mTOR, Ki: 1.42 nM
    Inhibitor 99.83%
CC-115 hydrochloride
mTOR, IC50: 21 nM
    Inhibitor 98.23%
NSC781406
mTOR, IC50: 5.4 nM
    Inhibitor 99.91%
GNE-493
mTOR, IC50: 30 nM
    Inhibitor 98.33%
WYE-687
mTOR, IC50: 7 nM
    Inhibitor 97.17%
PI3K-IN-22
mTOR, IC50: 0.6 nM
    Inhibitor
WYE-687 dihydrochloride
mTOR, IC50: 7 nM
    Inhibitor ≥98.0%
PI3Kα/mTOR-IN-1
mTOR, Ki: 10.6 nM
    Inhibitor