ATM

ATM Inhibitors (21)

ATM Related Products (21):

By Type:	Pan (7) Selective (14)

Cat. No.	Product Name	Effect	Purity

HY-111783

AZD-7648	Inhibitor	99.89%
AZD-7648 is a potent, orally active, selective DNA-PK inhibitor with an IC₅₀ of 0.6 nM.

HY-12016

KU-55933	Inhibitor	99.88%
KU-55933 is a potent ATM inhibitor with an IC₅₀ and K_i of 12.9 and 2.2 nM, respectively, and is highly selective for ATM as compared to DNA-PK, PI3K/PI4K, ATR and mTOR.

HY-109566

AZD1390	Inhibitor	99.97%
AZD1390 is a potent, highly selective, orally bioavailable, brain-penetrant ATM inhibitor with an IC₅₀ of 0.78 nM in cell.

HY-100016

AZD0156	Inhibitor	99.82%
AZD0156 is a potent, selective and orally active ATM inhibitor with an IC₅₀ of 0.58 nM.

HY-12061

KU-60019	Inhibitor	99.43%
KU-60019 is an improved ATM kinase-specific inhibitor with IC₅₀ of 6.3 nM.

HY-151915

ATR-IN-20

Inhibitor

ATR-IN-20 is a potent ATR (HY-14731

VE-821

Inhibitor 98.32%

VE-821 is a potent ATP-competitive inhibitor of ATR with K_i/IC₅₀ of 13 nM/26 nM.

HY-139609

Camonsertib

Inhibitor 99.75%

Camonsertib (RP-3500) is an orally active, selective ATR kinase inhibitor (ATRi) with an IC₅₀ of 1.00 nM in biochemical assays.

HY-112305

AZ32

Inhibitor 99.62%

AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC₅₀ of <6.2 nM for ATM enzyme, and an IC₅₀ of 0.31 μM for ATM in cell.

HY-15520

CGK733

Inhibitor 99.83%

CGK733 is a potent ATM/ATR inhibitor, used for the research of cancer.

HY-103241

Ro 90-7501

Inhibitor

Ro 90-7501 is an amyloid β₄₂ (Aβ₄₂) fibril assembly inhibitor that reduces Aβ₄₂-induced cytotoxicity (EC₅₀ of 2 μM).

HY-11002

CP-466722

Inhibitor 99.91%

CP-466722 is a rapidly reversible inhibitor of ATM, with an IC₅₀ of 4.1 μM, and has no effects on PI3K or closely related PI3K-like protein kinase (PIKK) family members.

HY-15521

ETP-46464

Inhibitor 99.55%

ETP-46464 is an effective mTOR and ATR inhibitor with IC₅₀s of 0.6 and 14 nM, respectively.

HY-150617

Lartesertib

Inhibitor 99.89%

Lartesertib [formula (1)] is a potent inhibitor of serine/threonine protein kinase ATM (extracted from patent WO2022058351A1).

HY-112198

AZ31

Inhibitor

AZ31 is a a potent, highly selective, and orally active ATM inhibitor with an IC₅₀ of <1.2 nM for ATM enzyme, and an IC₅₀ of 46 nM for ATM in cell.

HY-112614

ATM Inhibitor-1

Inhibitor

ATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibitor, with an IC₅₀ of 0.7 nM, shows weak activity against mTOR (IC₅₀, 21 μM), DNAPK (IC₅₀, 2.8 μM), PI3Kα (IC₅₀, 3.8 μM), PI3Kβ (IC₅₀, 10.3 μM), PI3Kγ (IC₅₀, 3 μM) and PI3Kδ (IC₅₀, 0.73 μM).

HY-144686

ATM Inhibitor-3

Inhibitor

ATM Inhibitor-3 (compound 34) is a potent and selective ATM inhibitor, with an IC₅₀ of 0.71 nM.

HY-144687

ATM Inhibitor-4

Inhibitor

ATM Inhibitor-4 (compound 39) is a potent and selective ATM inhibitor, with an IC₅₀ of 0.32 nM.

HY-147567

ATR-IN-15

Inhibitor

ATR-IN-15 (compound 1) is an orally active and potent ATR kinase inhibitor, with an IC₅₀ of 8 nM.

HY-144685

ATM Inhibitor-2

Inhibitor

ATM Inhibitor-2 (compound 7) is a potent and selective ATM inhibitor, with an IC₅₀ of <1 nM.

[email protected]

609-228-6898

Find Your Local Distributor

MedChemExpress
Contact Us
About Us
Headquarters
Distributors
Statement on False Report
Careers
Customer Support
Technical Support
Service
Ordering Information
Easy Return
Shipping Rates & Policies
Intellectual Property Promise
Resources
Free Sample
Literature
Molarity Calculator
Dilution Calculator
Terms & Conditions
Reconstitution Calculator
Specific Active Calculator

Subscribe to our E-newsletter

Name

Email *

Sorry, but the email address you supplied was invalid.

Thanks, your subscription has been confirmed. You will hear from us soon.

Submission failed, please try again later.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.

Copyright © 2013-2023 MedChemExpress. All Rights Reserved.

Site Map Privacy Policy

Join with us

As the situation with COVID-19 continues to unfold in every community, MedChemExpress is responding to the uncertainty caused by this outbreak thoughtfully and cautiously. Your need for high quality reagent doesn't stop during difficult times, and neither do we. We're doing our best to keep everyone healthy and safe in the workplace while also avoiding the interruptions to our day-to-day operations. If you need to change the delivery plan for items ordered, please contact us via email [email protected]. Thank you for being a loyal MedChemExpress customer, we are here to assist you as needed.