ATM Inhibitor-3
ATM Inhibitor-3 (compound 34) is a potent and selective ATM inhibitor, with an IC50 of 0.71 nM. ATM Inhibitor-3 shows inhibition of PI3K kinases family. ATM Inhibitor-3 exhibits favorable metabolic stability.
For research use only. We do not sell to patients.
- CAS No.: 2769140-52-3
- Formula: C25H29FN6O3
- Molecular Weight:480.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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ATM 0.71 nM (IC50) |
PI3K |
mTOR |
Chemical Information
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CAS No. 2769140-52-3
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Molecular Weight 480.53
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Formula C25H29FN6O3
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SMILES
COCCN1C(N(C2=C1C3=CC(C4=CC(F)=C(C=C4)NC(NCCN(C)C)=O)=CC=C3N=C2)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ATM Inhibitor-3 Related Classifications
HY-144686 Related Classifications
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