mTOR Inhibitors

mTOR

mTORC1

mTORC2

mTOR Inhibitors, Agonists, Activators, Modulators & Degraders

Product Name	mTOR	mTORC1	mTORC2	Purity
Rapamycin		mTOR, IC₅₀: 0.1 nM (in HEK293 cells )		99.94%
MHY1485		mTORC1	mTORC2	99.93%
Everolimus		mTOR, IC₅₀: 5-6 nM		99.85%
Torin 1	mTOR, IC₅₀: 3 nM	mTORC1, IC₅₀: 2-10 nM	mTORC2, IC₅₀: 2-10 nM	99.28%
AZD-8055	mTOR, IC₅₀: 0.8 nM			99.60%
Sapanisertib	mTOR, IC₅₀: 1 nM			99.88%
Salidroside	mTOR			99.88%
L-Leucine		mTORC1		99.79%
Temsirolimus		mTOR, IC₅₀: 1.76 μM		99.56%
Dactolisib	mTOR, IC₅₀: 20.7 nM			99.94%
Torin 2	mTOR, IC₅₀: 2.81 nM mTOR, EC₅₀: 0.25 nM (Cell Assay)			99.69%
Gedatolisib	mTOR, IC₅₀: 1.6 nM			99.89%
Dihydromyricetin		mTORC1	mTORC2	99.73%
Omipalisib		mTORC1, Ki: 0.18 nM	mTORC2, Ki: 0.3 nM	99.94%
PI-103		mTORC1, IC₅₀: 20 nM	mTORC2, IC₅₀: 83 nM	99.82%
JR-AB2-011			mTORC2, IC₅₀: 0.36 μM	98.15%
Camonsertib	mTOR, IC₅₀: 120 nM			99.99%
hSMG-1 inhibitor 11j	mTOR, IC₅₀: 50 nM			99.82%
Vistusertib	mTOR, IC₅₀: 2.81 nM			99.70%
Aloe emodin			mTORC2	98.32%
RMC-5552		mTORC1		99.94%
Torkinib	mTOR, IC₅₀: 8 nM	mTORC1, IC₅₀: 30 nM	mTORC2, IC₅₀: 58 nM	99.03%
Paxalisib	mTOR, Ki: 70 nM			99.51%
3BDO	mTOR			99.93%
RapaLink-1	mTOR			99.65%
Samotolisib	mTOR, IC₅₀: 165 nM			98.85%
PF-04691502	mTOR, Ki: 16 nM			99.33%
Apitolisib	mTOR, Ki: 17 nM			99.29%
KU-0063794		mTORC1, IC₅₀: 10 nM	mTORC2, IC₅₀: 10 nM	99.67%
hSMG-1 inhibitor 11e	mTOR, IC₅₀: 45 nM			99.94%
Bimiralisib	mTOR, IC₅₀: 89 nM			98.62%
BGT226	mTOR			99.85%
CC-115	mTOR, IC₅₀: 21 nM			99.10%
Dactolisib Tosylate	mTOR, IC₅₀: 20.7 nM			99.87%
OSI-027	mTOR, IC₅₀: 4 nM	mTORC1, IC₅₀: 22 nM	mTORC2, IC₅₀: 65 nM	99.95%
VS-5584	mTOR, IC₅₀: 37 nM			98.71%
ETP-46464	mTOR, IC₅₀: 0.6 nM			99.54%
Voxtalisib	mTOR, IC₅₀: 157 nM	mTORC1, IC₅₀: 160 nM	mTORC2, IC₅₀: 910 nM	99.82%
Ridaforolimus		mTOR		99.75%
WYE-132	mTOR, IC₅₀: 0.19 nM			99.90%
Onatasertib	mTOR, IC₅₀: 16 nM			99.47%
PP121	mTOR, IC₅₀: 10 nM			99.51%
GSK1059615	mTOR, IC₅₀: 12 nM			99.76%
GNE-317	mTOR			98.76%
PKI-402	mTOR, IC₅₀: 3 nM			99.17%
mTOR inhibitor-3	mTOR, Ki: 1.5 nM			99.79%
PF-04979064	mTOR, Ki: 1.42 nM			99.93%
Telocinobufagin	mTOR			99.93%
Hederacolchiside A1	mTOR			98.28%
PI-103 Hydrochloride		mTORC1, IC₅₀: 20 nM	mTORC2, IC₅₀: 83 nM	98.06%
CC-115 hydrochloride	mTOR, IC₅₀: 21 nM			98.01%
CZ415	mTOR, pIC₅₀: 8.07			98.39%
BGT226 maleate	mTOR			99.92%
(+)-Usnic acid		mTORC1	mTORC2	99.64%
Palomid 529		TORC1	TORC2	99.37%
GNE-493	mTOR, IC₅₀: 30 nM			99.81%
WAY-600	mTOR, IC₅₀: 9 nM			99.86%
HDACs/mTOR Inhibitor 1	mTOR, IC₅₀: 1.2 nM			99.01%
WYE-354	mTOR, IC₅₀: 5 nM			98.03%
Rotundic acid	mTOR			99.41%
PKI-179	mTOR, IC₅₀: 0.42 nM			98.0%
PQR620		mTORC1	mTORC2	98.01%
PQR530	mTOR, Kd: 0.33 nM			99.98%
GDC-0349	mTOR, Ki: 3.8 nM			99.10%
PI3K/mTOR Inhibitor-2	mTOR, IC₅₀: 4.7 nM			99.10%
XL388	mTOR, IC₅₀: 9.9 nM			99.57%
MTI-31	mTOR, Ki: 0.2 nM mTOR, IC₅₀: 39 nM (100 μM ATP)			99.98%
NSC781406	mTOR, IC₅₀: 5.4 nM			99.97%
GNE-477	mTOR, Ki: 21 nM			98.75%
mTOR inhibitor-8	mTOR			98.14%
Zederone	mTOR			99.61%
MT 63-78		mTORC1		98.11%
PI3K/mTOR Inhibitor-4	mTOR, IC₅₀: 13.85 nM
Pomiferin	mTOR, IC₅₀: 6.2 μM			98.01%
HTH-01-091	mTOR, IC₅₀: 632 nM			99.81%
8-Aminoadenosine	mTOR			99.05%
Succinylsulfathiazole	mTOR			99.22%
FT-1518		mTORC1	mTORC2	98.62%
GNE-490	mTOR, IC₅₀: 750 nM
AZD3147		mTORC1	mTORC2	99.93%
Rhodiolin	mTOR			98%
WYE-687	mTOR, IC₅₀: 7 nM			98.05%
TML-6	mTOR			98.34%
Darlifarnib		mTORC1
PI3K-IN-37	mTOR, IC₅₀: 4 nM			99.0%
PI3K-IN-22	mTOR, IC₅₀: 0.6 nM			99.50%
ETP-45658	mTOR, IC₅₀: 152.0 nM			98.97%
Phellodendrine	mTOR			99.60%
PKI-179 hydrochloride	mTOR, IC₅₀: 0.42 nM			99.66%
FD274	mTOR, IC₅₀: 2.03 nM			99.45%
Momordicine I	mTOR
SN32976	mTOR, IC₅₀: 194 nM			99.49%
PI3K/mTOR-IN-23 dihydrochloride	mTOR, IC₅₀: 41 nM			99.70%
WYE-687 dihydrochloride	mTOR, IC₅₀: 7 nM			≥98.0%
CC214-2		mTORC1	mTORC2	98.41%
Coronarin A		mTORC1		≥98.0%
PI3K/mTOR-IN-23	mTOR, IC₅₀: 49 nM			99.0%
FGF7p		mTORC1		99.34%
PI3Kα/mTOR-IN-1	mTOR, Ki: 10.6 nM			99.30%
HSP90/mTOR-IN-1	mTOR, IC₅₀: 29 nM
PI3K/mTOR Inhibitor-1	mTOR, IC₅₀: 186 nM
RMC-4745		mTORC1
mTOR inhibitor-2	mTOR, IC₅₀: 7 nM
Scoulerine hydrochloride	mTOR
PI3K/mTOR Inhibitor-9	mTOR, IC₅₀: 38 nM (phospho-S6 cellular assay) mTOR, IC₅₀: 16 nM (Ser240/244 cellular assay)
T133	mTOR, : 0.17
Anti-Mouse E-Cadherin/CD324 Antibody (DECMA-1)	mTOR
PF-05139962	mTOR, Ki: 5 nM
ATM Inhibitor-3	mTOR
DHW-221	mTOR, IC₅₀: 3.9 nM
ATM Inhibitor-4	mTOR
AGF347	mTOR
mTOR/HDAC-IN-1	mTOR, IC₅₀: 0.49 nM
PI3K/mTOR Inhibitor-3	mTOR
PI3Kα-IN-5	mTOR, IC₅₀: 3.3 nM
BIEGi-1		mTORC1
PI3K/mTOR-IN-19	mTOR, IC₅₀: 2.3 nM
CIDD 0067106		mTORC1
Tubulin-IN-64	mTOR
GP262	mTOR, Kd: 45.4 nM
PI3K/mTOR Inhibitor-12	mTOR, IC₅₀: 3.12 nM
mTORC1-IN-3		mTORC1, IC₅₀: 26.38 μM
eALM1137		mTORC1	mTORC2
PI3K/mTOR Inhibitor-8	mTOR, IC₅₀: 12 nM
PM54-1	mTOR
ATR-IN-20	mTOR, IC₅₀: 18 nM
Antifungal agent 106	mTOR, IC₅₀: 0.8 μM
M-1111		mTORC1
PI3K/mTOR Inhibitor-14	mTOR, IC₅₀: 10.1 nM
mTOR/HDAC6-IN-1	mTOR, IC₅₀: 133.7 nM
Nur77 modulator 3		mTORC1		99.01%
PI3K/mTOR-IN-17	mTOR, IC₅₀: 0.21 μM
NV-5440		mTORC1
Anti-inflammatory agent 107	mTOR
CC-M-1	mTOR, IC₅₀: 15 nM
4-TCPA	mTOR
mTOR inhibitor-13	mTOR, IC₅₀: 0.29 nM
mTOR inhibitor-17	mTOR, IC₅₀: 0.68 nM
mTOR inhibitor-16	mTOR, IC₅₀: 1.25 nM
SPR519	mTOR, IC₅₀: 0.01 μM
mTOR inhibitor-10	mTOR, IC₅₀: 0.7 nM
Succinylsulfathiazole (Standard)	mTOR
FBPase-IN-6		mTORC1

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