1. Signaling Pathways
  2. PI3K/Akt/mTOR
  3. mTOR
  4. mTOR Inhibitors

mTOR Inhibitors

mTOR

mTORC1

mTORC2

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

mTOR Inhibitors, Activators & Modulators
Product Name mTOR mTORC1 mTORC2 Purity
Rapamycin  
mTOR, IC50: 0.1 nM (in HEK293 cells )
  99.94%
Everolimus  
mTOR, IC50: 5-6 nM
  99.74%
MHY1485  
mTORC1
mTORC2
99.86%
Torin 1
mTOR, IC50: 3 nM
mTORC1, IC50: 2-10 nM
mTORC2, IC50: 2-10 nM
98.95%
AZD-8055
mTOR, IC50: 0.8 nM
    99.60%
HTH-01-091
mTOR, IC50: 632 nM
   
Dactolisib
mTOR, IC50: 20.7 nM
    99.94%
Sapanisertib
mTOR, IC50: 1 nM
    99.66%
JR-AB2-011    
mTORC2, IC50: 0.36 μM
98.53%
Salidroside
mTOR
    99.79%
Temsirolimus  
mTOR, IC50: 1.76 μM
  99.56%
3BDO
mTOR
    99.91%
Torin 2
mTOR, IC50: 2.81 nM
mTOR, EC50: 0.25 nM (Cell Assay)
    99.98%
L-Leucine  
mTORC1
  ≥98.0%
Torkinib
mTOR, IC50: 8 nM
mTORC1, IC50: 30 nM
mTORC2, IC50: 58 nM
98.37%
Omipalisib  
mTORC1, Ki: 0.18 nM
mTORC2, Ki: 0.3 nM
99.93%
Vistusertib
mTOR, IC50: 2.81 nM
    98.21%
PI-103  
mTORC1, IC50: 20 nM
mTORC2, IC50: 83 nM
98.93%
RapaLink-1
mTOR
    ≥98.0%
PF-04691502
mTOR, Ki: 16 nM
    99.64%
Dihydromyricetin  
mTORC1
mTORC2
99.79%
KU-0063794  
mTORC1, IC50: 10 nM
mTORC2, IC50: 10 nM
99.55%
Samotolisib
mTOR, IC50: 165 nM
    99.42%
Camonsertib
mTOR, IC50: 120 nM
    99.75%
Dactolisib Tosylate
mTOR, IC50: 20.7 nM
    99.88%
Ridaforolimus  
mTOR
  ≥98.0%
Bimiralisib
mTOR, IC50: 89 nM
    98.74%
RMC-5552  
mTORC1
  98.10%
OSI-027
mTOR, IC50: 4 nM
mTORC1, IC50: 22 nM
mTORC2, IC50: 65 nM
99.40%
Voxtalisib
mTOR, IC50: 157 nM
mTORC1, IC50: 160 nM
mTORC2, IC50: 910 nM
99.46%
Apitolisib
mTOR, Ki: 17 nM
    98.51%
PKI-402
mTOR, IC50: 3 nM
    98.43%
Gedatolisib
mTOR, IC50: 1.6 nM
    99.68%
BGT226 maleate
mTOR
    99.87%
CC-115
mTOR, IC50: 21 nM
    98.04%
VS-5584
mTOR, IC50: 37 nM
    98.15%
WYE-132
mTOR, IC50: 0.19 nM
    99.40%
PP121
mTOR, IC50: 10 nM
    99.08%
hSMG-1 inhibitor 11j
mTOR, IC50: 50 nM
    99.81%
GSK1059615
mTOR, IC50: 12 nM
    ≥99.0%
PQR530
mTOR, Kd: 0.33 nM
    99.93%
WYE-354
mTOR, IC50: 5 nM
    98.0%
CZ415
mTOR, pIC50: 8.07
    98.74%
GDC-0349
mTOR, Ki: 3.8 nM
    98.42%
GNE-317
mTOR
    99.31%
Palomid 529  
TORC1
TORC2
99.47%
mTOR inhibitor-3
mTOR, Ki: 1.5 nM
    99.08%
HDACs/mTOR Inhibitor 1
mTOR, IC50: 1.2 nM
    98.21%
Onatasertib
mTOR, IC50: 16 nM
   
ETP-46464
mTOR, IC50: 0.6 nM
    98.01%
PQR620  
mTORC1
mTORC2
WAY-600
mTOR, IC50: 9 nM
   
(+)-Usnic acid  
mTORC1
mTORC2
≥98.0%
CC-115 hydrochloride
mTOR, IC50: 21 nM
    98.23%
XL388
mTOR, IC50: 9.9 nM
    99.25%
PI3K/mTOR Inhibitor-2
mTOR, IC50: 4.7 nM
    98.25%
NSC781406
mTOR, IC50: 5.4 nM
    99.91%
Rotundic acid
mTOR
    99.41%
Arnicolide D
mTOR
    99.20%
PI-103 Hydrochloride  
mTORC1, IC50: 20 nM
mTORC2, IC50: 83 nM
98.00%
PF-04979064
mTOR, Ki: 1.42 nM
    99.83%
MT 63-78  
mTORC1
  98.22%
ETP-45658
mTOR, IC50: 152.0 nM
    98.05%
hSMG-1 inhibitor 11e
mTOR, IC50: 45 nM
    99.18%
GNE-493
mTOR, IC50: 30 nM
    98.33%
GNE-477
mTOR, Ki: 21 nM
    98.70%
mTOR inhibitor-8
mTOR
    98.04%
PKI-179 hydrochloride
mTOR, IC50: 0.42 nM
    98.11%
PKI-179
mTOR, IC50: 0.42 nM
    ≥98.0%
WYE-687
mTOR, IC50: 7 nM
    98.10%
GNE-490
mTOR, IC50: 750 nM
   
BGT226
mTOR
   
TML-6
mTOR
    98.34%
Pomiferin
mTOR, IC50: 6.2 μM
   
Hederacolchiside A1
mTOR
    99.69%
MTI-31
mTOR, Ki: 0.2 nM
mTOR, IC50: 39 nM (100 μM ATP)
    99.94%
PI3K/mTOR Inhibitor-4
mTOR, IC50: 13.85 nM
   
PI3K/mTOR Inhibitor-1
mTOR, IC50: 186 nM
   
FT-1518  
mTORC1
mTORC2
98.14%
mTOR inhibitor-2
mTOR, IC50: 7 nM
   
PI3K-IN-37
mTOR, IC50: 4 nM
   
PI3K/mTOR Inhibitor-9
mTOR, IC50: 38 nM (phospho-S6 cellular assay)
mTOR, IC50: 16 nM (Ser240/244 cellular assay)
   
PI3K-IN-22
mTOR, IC50: 0.6 nM
   
ATM Inhibitor-3
mTOR
   
ATM Inhibitor-4
mTOR
   
mTOR/HDAC-IN-1
mTOR, IC50: 0.49 nM
   
PI3K/mTOR Inhibitor-3
mTOR
   
PI3Ka-IN-5
mTOR, IC50: 3.3 nM
   
WYE-687 dihydrochloride
mTOR, IC50: 7 nM
    ≥98.0%
Coronarin A  
mTORC1
 
PI3Kα-IN-5
mTOR, IC50: 3.3 nM
   
AZD3147  
mTORC1
mTORC2
PI3K/mTOR Inhibitor-8
mTOR, IC50: 12 nM
   
8-Aminoadenosine
mTOR
   
HSP90/mTOR-IN-1
mTOR, IC50: 29 nM
   
mTOR/HDAC6-IN-1
mTOR, IC50: 133.7 nM
   
PI3Kα/mTOR-IN-1
mTOR, Ki: 10.6 nM