2769140-52-3
2769140-52-3
Chemical Structure
ATM Inhibitor-3
- CAS No.: 2769140-52-3
- Formula:C25H29FN6O3
- Molecular Weight:480.53
IUPAC Name: 1-(2-(dimethylamino)ethyl)-3-(2-fluoro-4-(1-(2-methoxyethyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinolin-8-yl)phenyl)urea
InChIKey: LDAMATOMTKLLAD-UHFFFAOYSA-N
SMILES: COCCN1C(N(C2=C1C3=CC(C4=CC(F)=C(C=C4)NC(NCCN(C)C)=O)=CC=C3N=C2)C)=O
Biological Activity: ATM Inhibitor-3 (compound 34) is a potent and selective ATM inhibitor, with an IC50 of 0.71 nM. ATM Inhibitor-3 shows inhibition of PI3K kinases family. ATM Inhibitor-3 exhibits favorable metabolic stability[1].
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ATM Inhibitor-3 | ATM Inhibitor-3 (compound 34) is a potent and selective ATM inhibitor, with an IC50 of 0.71 nM. ATM Inhibitor-3 shows inhibition of PI3K kinases family. ATM Inhibitor-3 exhibits favorable metabolic stability. | |||||||||||||||||||||
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