2230820-11-6
2230820-11-6
Chemical Structure
AZD-7648
- CAS No.: 2230820-11-6
- Formula:C18H20N8O2
- Molecular Weight:380.40
IUPAC Name: 7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one
InChIKey: XISVSTPEXYIKJL-UHFFFAOYSA-N
SMILES: CC1=CC2=NC=NN2C=C1NC3=NC=C(N(C)C(N4C5CCOCC5)=O)C4=N3
Biological Activity: AZD-7648 is a potent, orally active, selective DNA-PK inhibitor with an IC50 of 0.6 nM. AZD-7648 induces apoptosis and shows antitumor activity[1].
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AZD-7648 | 99.86% | AZD-7648 is a potent, orally active, selective DNA-PK inhibitor with an IC50 of 0.6 nM. AZD-7648 induces apoptosis and shows antitumor activity. | ||||||||||||||||||||
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AZD-7648 (GMP) | AZD-7648 (GMP) is AZD-7648 (HY-111783) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. AZD-7648 is a potent, orally active, selective DNA-PK inhibitor with an IC50 of 0.6 nM. AZD-7648 induces apoptosis and shows antitumor activity. | |||||||||||||||||||||
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AZD-7648 (Standard) | ≥98% | AZD-7648 (Standard) is the analytical standard of AZD-7648 (HY-111783). This product is intended for research and analytical applications. AZD-7648 is a potent, orally active, selective DNA-PK inhibitor with an IC50 of 0.6 nM. AZD-7648 induces apoptosis and shows antitumor activity. | ||||||||||||||||||||
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