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  2. GsMTx4

GsMTx4 

Cat. No.: HY-P1410
Handling Instructions

GsMTx4 is a spider venom peptide that selectively inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology. GsMTx4 significantly attenuates bladder hyperactivity.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

GsMTx4 Chemical Structure

GsMTx4 Chemical Structure

CAS No. : 1209500-46-8

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500 μg USD 270 Ask For Quote & Lead Time
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Description

GsMTx4 is a spider venom peptide that selectively inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology[1]. GsMTx4 significantly attenuates bladder hyperactivity[2].

IC50 & Target

MSCs[1]

Molecular Weight

4101.89

Formula

C₁₈₅H₂₇₉N₄₉O₄₅S₆

CAS No.

1209500-46-8

Sequence

Gly-Cys-Leu-Glu-Phe-Trp-Trp-Lys-Cys-Asn-Pro-Asn-Asp-Asp-Lys-Cys-Cys-Arg-Pro-Lys-Leu-Lys-Cys-Ser-Lys-Leu-Phe-Lys-Leu-Cys-Asn-Phe-Ser-Phe

Sequence Shortening

GCLEFWWKCNPNDDKCCRPKLKCSKLFKLCNFSF

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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GsMTx4
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HY-P1410
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