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  2. GsMTx4 (TFA)

GsMTx4 (TFA) 

Cat. No.: HY-P1410A Purity: 97.71%
Handling Instructions

GsMTx4 TFA is a spider venom peptide that selectively inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 TFA is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology. GsMTx4 TFA significantly attenuates bladder hyperactivity.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

GsMTx4 (TFA) Chemical Structure

GsMTx4 (TFA) Chemical Structure

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 16695 In-stock
Estimated Time of Arrival: December 31
500 μg USD 270 In-stock
Estimated Time of Arrival: December 31
1 mg USD 500 In-stock
Estimated Time of Arrival: December 31
5 mg USD 1800 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

GsMTx4 TFA is a spider venom peptide that selectively inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 TFA is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology[1]. GsMTx4 TFA significantly attenuates bladder hyperactivity[2].

IC50 & Target

MSCs[1]

Molecular Weight

4215.91

Formula

C₁₈₇H₂₈₀N₄₉F₃O₄₇S₆

Sequence

Gly-Cys-Leu-Glu-Phe-Trp-Trp-Lys-Cys-Asn-Pro-Asn-Asp-Asp-Lys-Cys-Cys-Arg-Pro-Lys-Leu-Lys-Cys-Ser-Lys-Leu-Phe-Lys-Leu-Cys-Asn-Phe-Ser-Phe

Sequence Shortening

GCLEFWWKCNPNDDKCCRPKLKCSKLFKLCNFSF

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
References
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GsMTx4 (TFA)
Cat. No.:
HY-P1410A
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