Sunitinib

(Synonyms: SU 11248)
96 Cited Publications
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Based on 96 publication(s) in Google Scholar

Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively. Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation.

For research use only. We do not sell to patients.

  • Purity: 99.04%
  • CAS No.: 557795-19-4
  • Formula: C22H27FN4O2
  • Molecular Weight:398.47
  • Storage:

    4°C, protect from light

    * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

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All PDGFR Isoforms

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