1. Signaling Pathways
  2. Protein Tyrosine Kinase/RTK
  3. VEGFR
  4. VEGFR2/KDR/Flk-1 Inhibitors

VEGFR2/KDR/Flk-1 Inhibitors

VEGFR1/Flt-1

VEGFR2/KDR/Flk-1

VEGFR3/Flt-4

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform VEGFR2/KDR/Flk-1 together.

Please try each isoform separately.

VEGFR2/KDR/Flk-1 Specific Inhibitors & Antagonists
Product Name VEGFR2/KDR/Flk-1 VEGFR1/Flt-1 VEGFR3/Flt-4 VEGFR2/KDR/Flk-1 Selectivity Purity
Cabozantinib
VEGFR2, IC50: 0.035 nM
Flt-1, IC50: 12 nM
Flt-4, IC50: 6 nM
Selective Inhibitor 99.92%
Semaxinib
Flk-1, IC50: 1.23 μM
    Selective Inhibitor 99.96%
Sunitinib
VEGFR2, IC50: 80 nM
    Selective Inhibitor 99.66%
Apatinib
VEGFR2, IC50: 1 nM
    Selective Inhibitor 99.93%
SU 5402
VEGFR2, IC50: 20 nM
    Selective Inhibitor 99.39%
RAF265
VEGFR2
    Selective Inhibitor 99.98%
Sunitinib Malate
VEGFR2, IC50: 80 nM
    Selective Inhibitor 99.47%
Cabozantinib S-malate
VEGFR2, IC50: 0.035 nM
    Selective Inhibitor 99.93%
5Z-7-Oxozeaenol
VEGFR-2, IC50: 52 nM
 
VEGFR-3, IC50: 110 nM
Selective Inhibitor >99.0%
Vatalanib dihydrochloride
VEGFR2, IC50: 37 nM
    Selective Inhibitor 99.86%
Brivanib
VEGFR2, IC50: 25 nM
    Selective Inhibitor 99.37%
Altiratinib
VEGFR2, IC50: 9.2 nM
    Selective Inhibitor 95.95%
PP121
VEGFR2, IC50: 12 nM
    Selective Inhibitor 98.89%
Golvatinib
VEGFR2, IC50: 16 nM
    Selective Inhibitor 99.29%
Ki8751
VEGFR2, IC50: 0.9 nM
    Selective Inhibitor 98.97%
Ningetinib
VEGFR2, IC50: 1.9 nM
    Selective Inhibitor 98.75%
ZM323881 hydrochloride
VEGFR2, IC50: 2 nM
    Selective Inhibitor 99.52%
Toceranib phosphate
Flk-1, Ki: 6 nM
    Selective Inhibitor 98.43%
Toceranib
Flk-1, Ki: 6 nM
    Selective Inhibitor 96.50%
SU5408
VEGFR2, IC50: 70 nM
    Selective Inhibitor >98.0%
CGP60474
VEGFR-2, IC50: 84 nM
    Selective Inhibitor 99.88%
SKLB1002
VEGFR2, IC50: 32 nM
    Selective Inhibitor 98.04%
ZM 306416
KDR, IC50: 100 nM
Flt-1, IC50: 2 μM
  Selective Inhibitor 99.80%
Brivanib alaninate
VEGFR2, IC50: 25 nM
    Selective Inhibitor 99.76%
AZD2932
VEGFR2, IC50: 8 nM
    Selective Inhibitor 98.12%
BFH772
VEGFR2, IC50: 3 nM
    Selective Inhibitor 96.38%
NVP-ACC789
VEGFR-2, IC50: 0.02 μM
mVEGFR-2, IC50: 0.23 μM
VEGFR-1, IC50: 0.38 μM
VEGFR-3, IC50: 0.18 μM
Selective Inhibitor 99.58%
Ramucirumab
VEGFR-2
    Selective Antagonist
NVP-BAW2881
VEGFR2, IC50: 9 nM
VEGFR1, IC50: 820 nM
VEGFR3, IC50: 420 nM
Selective Inhibitor 98.42%
Ningetinib Tosylate
VEGFR2, IC50: 1.9 nM
    Selective Inhibitor 99.88%
BMS-794833
VEGFR2, IC50: 15 nM
    Selective Inhibitor 99.82%
Vandetanib hydrochloride
VEGFR2, IC50: 40 nM
    Selective Inhibitor
WHI-P180
KDR, IC50: 66 nM
    Selective Inhibitor 99.76%
ZD-4190
VEGFR2
    Selective Inhibitor 99.20%
MGCD-265 analog
VEGFR2, IC50: 10 nM
    Selective Inhibitor 96.53%
R916562
VEGF-R2, IC50: 24 nM
    Selective Inhibitor
Vatalanib free base
VEGFR2, IC50: 37 nM
    Selective Inhibitor
WHI-P180 hydrochloride
KDR, IC50: 66 nM
    Selective Inhibitor
ZM323881
VEGFR2, IC50: 2 nM
    Selective Inhibitor
ZK-261991
VEGFR2, IC50: 5 nM
    Selective Inhibitor
TAS-115
VEGFR2, IC50: 30 nM
    Selective Inhibitor
Vandetanib trifluoroacetate
VEGFR2, IC50: 40 nM
    Selective Inhibitor
KDR-in-4
KDR, IC50: 7 nM
    Selective Inhibitor
Sorafenib
VEGFR2, IC50: 90 nM
 
VEGFR3, IC50: 20 nM
Pan Inhibitor 99.92%
Nintedanib
VEGFR2, IC50: 13 nM
VEGFR1, IC50: 34 nM
VEGFR3, IC50: 13 nM
Pan Inhibitor 99.97%
Lenvatinib
VEGFR2, IC50: 4 nM
VEGFR1, IC50: 22 nM
VEGFR3, IC50: 5.2 nM
Pan Inhibitor 99.74%
Regorafenib
VEGFR2, IC50: 4.2 nM
VEGFR1, IC50: 13 nM
VEGFR3, IC50: 46 nM
Pan Inhibitor 99.96%
Ilorasertib hydrochloride
VEGFR2, IC50: 2 nM
VEGFR1, IC50: 1 nM
VEGFR3, IC50: 43 nM
Pan Inhibitor
Sorafenib Tosylate
VEGFR2, IC50: 90 nM
 
VEGFR3, IC50: 20 nM
Pan Inhibitor 99.53%
Axitinib
VEGFR2, IC50: 0.2 nM
VEGFR1, IC50: 0.1 nM
VEGFR3, IC50: 0.1 nM
Pan Inhibitor 99.94%
PD173074
VEGFR2, IC50: 100 nM
    Pan Inhibitor 99.55%
Cediranib
KDR, IC50: 1 nM
Flt-1, IC50: 5 nM
Flt-4, IC50: 3 nM
Pan Inhibitor 99.58%
Nintedanib esylate
VEGFR2, IC50: 13 nM
VEGFR1, IC50: 34 nM
VEGFR3, IC50: 13 nM
Pan Inhibitor 99.95%
Sitravatinib
VEGFR2, IC50: 5 nM
VEGFR1, IC50: 6 nM
VEGFR3, IC50: 2 nM
Pan Inhibitor 99.85%
Lucitanib
VEGFR2, IC50: 25 nM
VEGFR1, IC50: 7 nM
VEGFR3, IC50: 10 nM
Pan Inhibitor 98.24%
Tivozanib
VEGFR2, IC50: 6.5 nM
VEGFR1, IC50: 30 nM
VEGFR3, IC50: 15 nM
Pan Inhibitor 99.52%
Gandotinib
KDR, IC50: 109 nM
 
Flt-4, IC50: 25 nM
Pan Inhibitor 99.96%
SU14813
VEGFR2, IC50: 50 nM
VEGFR1, IC50: 2 nM
  Pan Inhibitor 95.74%
Regorafenib Hydrochloride
VEGFR2, IC50: 4.2 nM
VEGFR1, IC50: 13 nM
VEGFR3, IC50: 46 nM
Pan Inhibitor 99.58%
Pazopanib Hydrochloride
VEGFR2, IC50: 30 nM
VEGFR1, IC50: 10 nM
VEGFR3, IC50: 47 nM
Pan Inhibitor 99.83%
Motesanib
VEGFR2, IC50: 3 nM
VEGFR1, IC50: 2 nM
VEGFR3, IC50: 6 nM
Pan Inhibitor 99.75%
Telatinib
VEGFR2, IC50: 6 nM
 
VEGFR3, IC50: 4 nM
Pan Inhibitor 99.49%
TAK-593
VEGFR2, IC50: 0.95 nM
VEGFR1, IC50: 3.2 nM
VEGFR3, IC50: 1.1 nM
Pan Inhibitor 99.62%
Regorafenib monohydrate
VEGFR2, IC50: 4.2 nM
VEGFR1, IC50: 13 nM
VEGFR3, IC50: 46 nM
Pan Inhibitor 99.96%
Tesevatinib
KDR, IC50: 1.5 nM
 
Flt-4, IC50: 8.7 nM
Pan Inhibitor 99.21%
Fruquintinib
VEGFR2, IC50: 35 nM
VEGFR1, IC50: 33 nM
VEGFR3, IC50: 0.5 nM
Pan Inhibitor 99.93%
SU1498
Flk-1, IC50: 700 nM
    Pan Inhibitor 99.46%
Cediranib maleate
KDR, IC50: 1 nM
Flt-1, IC50: 5 nM
Flt-4, IC50: 3 nM
Pan Inhibitor 96.67%
SU14813 maleate
VEGFR2, IC50: 50 nM
VEGFR1, IC50: 2 nM
  Pan Inhibitor 99.34%
Motesanib Diphosphate
VEGFR2, IC50: 3 nM
VEGFR1, IC50: 2 nM
VEGFR3, IC50: 6 nM
Pan Inhibitor 99.64%
CP-547632
VEGFR-2, IC50: 11 nM
    Pan Inhibitor >99.0%
ACTB-1003
VEGFR2, IC50: 2 nM
    Pan Inhibitor 97.65%
Acrizanib
VEGFR-2, IC50: 17.4 nM
    Pan Inhibitor 99.84%
KRN-633
VEGFR2, IC50: 160 nM
VEGFR1, IC50: 170 nM
VEGFR3, IC50: 125 nM
Pan Inhibitor 99.06%
CP-547632 hydrochloride
VEGFR-2, IC50: 11 nM
    Pan Inhibitor
Ilorasertib
VEGFR2, IC50: 2 nM
VEGFR1, IC50: 1 nM
VEGFR3, IC50: 43 nM
Pan Inhibitor
Tyrosine kinase-IN-1
KDR, IC50: 20 nM
Flt-1, IC50: 4 nM
  Pan Inhibitor 99.47%
Lenvatinib mesylate
VEGFR2, IC50: 4 nM
VEGFR1, IC50: 22 nM
VEGFR3, IC50: 5.2 nM
Pan Inhibitor
ODM-203
VEGFR2, IC50: 9 nM
VEGFR1, IC50: 26 nM
VEGFR3, IC50: 5 nM
Pan Inhibitor
(Z)-Guggulsterone
VEGF-R2
    Pan Inhibitor
Sulfatinib
VEGFR2
VEGFR1
VEGFR3
default Inhibitor 97.97%
JI-101
VEGFR2
    default Inhibitor 99.95%