1. Signaling Pathways
  2. Protein Tyrosine Kinase/RTK
  3. PDGFR
  4. PDGFRα Inhibitors

PDGFRα Inhibitors

PDGFR

PDGFRβ

PDGFRα

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Sorry. There is currently no product that acts on isoform PDGFRα together.

Please try each isoform separately.

PDGFRα Specific Inhibitors
Product Name PDGFRα PDGFRβ PDGFRα Selectivity Purity
Telatinib mesylate
PDGFRα, IC50: 15 nM
  Selective Inhibitor
Ripretinib
PDGFRA
  Selective Inhibitor 99.46%
Amuvatinib
PDGFRαV561D, IC50: 40 nM
PDGFRαD842V, IC50: 81 nM
  Selective Inhibitor 99.36%
ENMD-2076
PDGFRα, IC50: 56.4 nM
  Selective Inhibitor 99.23%
ENMD-2076 Tartrate
PDGFRα, IC50: 56.4 nM
  Selective Inhibitor 98.59%
PDGFRα kinase inhibitor 1
PDGFRα, IC50: 132 nM
PDGFRβ, IC50: 6115 nM
Selective Inhibitor 99.90%
Tyrosine kinase-IN-1
PDGFRα, IC50: 4 nM
  Selective Inhibitor 99.47%
Amuvatinib hydrochloride
PDGFRαV561D, IC50: 40 nM
PDGFRαD842V, IC50: 81 nM
  Selective Inhibitor
Lenvatinib
PDGFRα, IC50: 51 nM
PDGFRβ, IC50: 39 nM
Pan Inhibitor 99.74%
Nintedanib
PDGFRα, IC50: 59 nM
PDGFRβ, IC50: 65 nM
Pan Inhibitor 99.97%
Ponatinib
PDGFRα, IC50: 1.1 nM
  Pan Inhibitor 99.13%
Crenolanib
PDGFRα, Kd: 2.1 nM
PDGFRβ, Kd: 3.2 nM
Pan Inhibitor 99.67%
Cediranib
PDGFRα, IC50: 36 nM
PDGFRβ, IC50: 5 nM
Pan Inhibitor 99.58%
CP-673451
PDGFRα, IC50: 10 nM
PDGFRβ, IC50: 1 nM
Pan Inhibitor 99.65%
Nintedanib esylate
PDGFRα, IC50: 59 nM
PDGFRβ, IC50: 65 nM
Pan Inhibitor 99.93%
Dovitinib
PDGFRα, IC50: 27 nM
PDGFRβ, IC50: 210 nM
Pan Inhibitor 97.18%
Telatinib
PDGFRα, IC50: 15 nM
  Pan Inhibitor 99.49%
Ilorasertib hydrochloride
PDGFRα, IC50: 11 nM
PDGFRβ, IC50: 13 nM
Pan Inhibitor 98.91%
TAK-593
PDGFRα, IC50: 4.3 nM
PDGFRαV561D, IC50: 1 nM
PDGFRβ, IC50: 13 nM
Pan Inhibitor 99.62%
Cediranib maleate
PDGFRα, IC50: 36 nM
PDGFRβ, IC50: 5 nM
Pan Inhibitor 96.67%
AC710
PDGFRα, Kd: 1.3 nM
PDGFRβ, Kd: 1 nM
Pan Inhibitor 98.03%
JNJ-​10198409
PDGFRα, IC50: 45 nM
PDGFRβ, IC50: 4.2 nM
Pan Inhibitor >99.0%
Ilorasertib
PDGFRα, IC50: 11 nM
PDGFRβ, IC50: 13 nM
Pan Inhibitor
Lenvatinib mesylate
PDGFRα, IC50: 51 nM
PDGFRβ, IC50: 39 nM
Pan Inhibitor
GZD856
PDGFRα, IC50: 68.6 nM
PDGFRβ, IC50: 136.6 nM
Pan Inhibitor
Hypothemycin
PDGFRα, Ki: 1.5 μM
PDGFRβ, Ki: 900 nM
Pan Inhibitor
HG-7-85-01
PDGFRα, IC50: 440 nM
  Pan Inhibitor
Ponatinib D8
PDGFRα, IC50: 1.1 nM
  Pan Inhibitor
AC710 Mesylate
PDGFRα, Kd: 1.3 nM
PDGFRβ, Kd: 1 nM
Pan Inhibitor