288383-20-0
288383-20-0
Chemical Structure
Cediranib
Synonym(s): AZD2171
- CAS No.: 288383-20-0
- Formula:C25H27FN4O3
- Molecular Weight:450.51
IUPAC Name: 4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline
InChIKey: XXJWYDDUDKYVKI-UHFFFAOYSA-N
SMILES: FC1=C(OC2=C(C(C=C3OCCCN4CCCC4)=NC=N2)C=C3OC)C=CC5=C1C=C(C)N5
Biological Activity: Cediranib (AZD2171) is a highly potent, orally available and blood-brain barrier permeability VEGFR tyrosine kinase inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cediranib | 99.87% | Cediranib (AZD2171) is a highly potent, orally available and blood-brain barrier permeability VEGFR tyrosine kinase inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively. | ||||||||||||||||||||
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Cediranib (Standard) | ≥98% | Cediranib (Standard) is the analytical standard of Cediranib. This product is intended for research and analytical applications. Cediranib (AZD2171) is a highly potent, orally available VEGFR tyrosine kinase inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively. | ||||||||||||||||||||
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