2. Signaling Pathways
  3. MAPK/ERK Pathway
  4. MNK
  5. MNK1 Isoform

MNK1

 

MNK1 Related Products (6):

Cat. No. Product Name Effect Purity
  • HY-100022
    Tomivosertib
    		Inhibitor 99.92%
    Tomivosertib (eFT508) is a potent, highly selective, and orally active MNK1 and MNK2 inhibitor, with IC50s of 1-2 nM against both isoforms.
  • HY-10520
    CGP 57380
    		Inhibitor 98.0%
    CGP 57380 is a cell-permeable pyrazolo-pyrimidine compound that acts as a selective inhibitor of Mnk1 with IC50 of 2.2 μM, but has no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases.
  • HY-112424
    Tinodasertib
    		Inhibitor 99.57%
    Tinodasertib (ETC-206) is a selective MNK1 and MNK2 inhibitor with IC50s of 64 nM and 86 nM, respectively.
  • HY-112113
    SLV-2436
    		Inhibitor 98.47%
    SLV-2436 is a highly potent and ATP-competitive inhibitor of MNK1 and MNK2 with IC50s of 10.8  nM and 5.4 nM, respectively.
  • HY-146805
    EB1
    		Inhibitor
    EB1 is the inhibitor of kinases MNK with IC50s of 0.69 μM (MNK1) and 9.4 μM (MNK2).
  • HY-146735
    MNK1/2-IN-6
    		Inhibitor
    MNK1/2-IN-6 is a potent and selective MNK1/2 inhibitor with IC50s of 2.3 nM and 3.4 nM for MNK1 and MNK2, respectively.