2771087-94-4
2771087-94-4
Chemical Structure
MNK1/2-IN-6
- CAS No.: 2771087-94-4
- Formula:C27H24N6O
- Molecular Weight:448.52
IUPAC Name: (S)-(3-aminopiperidin-1-yl)(4-(3-(isoquinolin-6-yl)imidazo[1,2-b]pyridazin-6-yl)phenyl)methanone
InChIKey: RKNGTCDEHZFRSK-QHCPKHFHSA-N
SMILES: N[C@H]1CCCN(C1)C(C2=CC=C(C=C2)C3=NN4C(C5=CC=C6C=NC=CC6=C5)=CN=C4C=C3)=O
Biological Activity: MNK1/2-IN-6 is a potent and selective MNK1/2 inhibitor with IC50s of 2.3 nM and 3.4 nM for MNK1 and MNK2, respectively. MNK1/2-IN-6 induces apoptosis in a concentration-dependent manner[1].
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MNK1/2-IN-6 | MNK1/2-IN-6 is a potent and selective MNK1/2 inhibitor with IC50s of 2.3 nM and 3.4 nM for MNK1 and MNK2, respectively. MNK1/2-IN-6 induces apoptosis in a concentration-dependent manner. | |||||||||||||||||||||
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References
Keywords
