ETP-45835
ETP-45835 is slective and potent MNK inhibitor with IC50s of 575 nM and 646 nM for MNK1 and MNK2, respectively. ETP-45835 shows little activity against 24 other kinases. ETP-45835 inhibits eIF4E Ser209 phosphorylation in cells, and has anticancer effects.
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- CAS. Nr.: 794510-70-6
- Formel: C13H16N4
- Molecular Weight:228.29
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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MNK1 575 nM (IC50) |
MNK2 646 nM (IC50) |
Chemical Information
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CAS. Nr. 794510-70-6
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Molecular Weight 228.29
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Formel C13H16N4
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SMILES
N=1C=CC(=CC1)C2=NNC(=C2)C3CCNCC3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)