1464150-99-9
1464150-99-9
Chemical Structure
ETC-168
- CAS No.: 1464150-99-9
- Formula:C24H19N5O2
- Molecular Weight:409.44
InChIKey: CARBAQLLNJEQRM-UHFFFAOYSA-N
SMILES: N#CC1=CC=C(C2=CN=C3C=CC(C4=CC=C(C(N5CCOCC5)=O)C=C4)=NN32)C=C1
Biological Activity: ETC-168 is a selective and oral active MNK inhibitor with the IC50 values of 23 and 43 nM against MNK1 and MNK2, respectively. ETC-168 shows antiproliferative efficacy in vivo and in vitro[1].
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ETC-168 | ETC-168 is a selective and oral active MNK inhibitor with the IC50 values of 23 and 43 nM against MNK1 and MNK2, respectively. ETC-168 shows antiproliferative efficacy in vivo and in vitro. | |||||||||||||||||||||
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References
Keywords
