GSK190937
GSK190937 is a type II platelet-derived growth factor receptor alpha (PDGFRA) human kinase inhibitor with antimalarial activity. GSK190937 can inhibit the formation of hemozoin in the malaria parasite, resulting in the accumulation of free hemoglobin within the malaria parasite. GSK190937 shows IC50 values of 0.22, 0.59 and 0.25 μM against P. falciparum NF54, K1 and Dd2 parasite. GSK190937 shows an IC50 of 25 μM for CHO cells. GSK190937 can be used for research of malaria.
For research use only. We do not sell to patients.
- CAS No.: 2651234-01-2
- Formula: C22H20Cl2N4O
- Molecular Weight:427.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
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PDGFRα |
Chemical Information
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CAS No. 2651234-01-2
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Molecular Weight 427.33
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Formula C22H20Cl2N4O
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SMILES
CC1=CN=C(N)C(/C=C/C2=CN=CC(C(NCCC3=C(Cl)C=C(Cl)C=C3)=O)=C2)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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