2590556-80-0
2590556-80-0
Chemical Structure
Velzatinib
Synonym(s): M4205; IDRX-42
- CAS No.: 2590556-80-0
- Formula:C29H32N8O
- Molecular Weight:508.62
IUPAC Name: N-(4-(1-methyl-1H-pyrazol-4-yl)benzyl)-6-(7-(3-(pyrrolidin-1-yl)propoxy)imidazo[1,2-a]pyridin-3-yl)pyrimidin-4-amine
InChIKey: LVMAULGVWBINFP-UHFFFAOYSA-N
SMILES: CN1N=CC(C2=CC=C(CNC3=NC=NC(C4=CN=C5C=C(C=CN54)OCCCN6CCCC6)=C3)C=C2)=C1
Biological Activity: Velzatinib (M4205) is a multi-target inhibitor for PDGFRB, PDGFRA, CSF1R, c-Kit, FLT3, and LCK, with an IC50s of 2.6, 50, 5.5, 44, 141 and 141 nM, respectively. Velzatinib exhibits antitumor efficacy in xenograft mouse models[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Velzatinib | 99.40% | Velzatinib (M4205) is a multi-target inhibitor for PDGFRB, PDGFRA, CSF1R, c-Kit, FLT3, and LCK, with an IC50s of 2.6, 50, 5.5, 44, 141 and 141 nM, respectively. Velzatinib exhibits antitumor efficacy in xenograft mouse models. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.54
HY-182004FLT3-IN-40 -
Similarity Score 0.51
HY-101029RMBM-55 (Standard) -
Similarity Score 0.51
HY-101030MBM-17 -
Similarity Score 0.49
HY-13418GDorsomorphin dihydrochloride (GMP) -
Similarity Score 0.49
HY-160787NCGC1481 -
Similarity Score 0.49
HY-164394EMD 1204831 -
Similarity Score 0.49
HY-145269AL-GDa62 -
Similarity Score 0.49
HY-13418ADorsomorphin -
Similarity Score 0.48
HY-173191SK-124 -
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