1. PI3K/Akt/mTOR
  2. mTOR
    PI3K

GDC-0084 (Synonyms: RG7666)

Cat. No.: HY-19962 Purity: 99.54%
Data Sheet SDS Handling Instructions

GDC-0084 is a potent, selective inhibitor of Class I PI3K and mTOR with good penetration across the blood-brain barrier.

For research use only. We do not sell to patients.
GDC-0084 Chemical Structure

GDC-0084 Chemical Structure

CAS No. : 1382979-44-3

Size Price Stock Quantity
10 mM * 1 mL in DMSO $93 In-stock
1 mg $60 In-stock
5 mg $110 In-stock
10 mg $160 In-stock
50 mg $540 In-stock
100 mg $950 In-stock
200 mg   Get quote  
500 mg   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

GDC-0084 is a potent, selective inhibitor of Class I PI3K and mTOR with good penetration across the blood-brain barrier.[1] [2] target : PI3K, mToR

Clinical Trial
NCT Number Sponsor Condition Start Date Phase
NCT01547546 Genentech, Inc. Glioblastoma, Glioma April 2012 Phase 1
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References
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.6149 mL 13.0746 mL 26.1493 mL
5 mM 0.5230 mL 2.6149 mL 5.2299 mL
10 mM 0.2615 mL 1.3075 mL 2.6149 mL
References
Molecular Weight

382.42

Formula

C₁₈H₂₂N₈O₂

CAS No.

1382979-44-3

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: 6 mg/mL (Need ultrasonic)

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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GDC-0084
Cat. No.:
HY-19962
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