1222998-36-8
1222998-36-8
Chemical Structure
Torin 1
- CAS No.: 1222998-36-8
- Formula:C35H28F3N5O2
- Molecular Weight:607.62
IUPAC Name: 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one
InChIKey: AKCRNFFTGXBONI-UHFFFAOYSA-N
SMILES: O=C1N(C2=C(C=C1)C=NC3=CC=C(C=C32)C4=CC5=CC=CC=C5N=C4)C6=CC=C(C(C(F)(F)F)=C6)N7CCN(CC7)C(CC)=O
Biological Activity: Torin 1 is a potent inhibitor of mTOR with an IC50 of 3 nM. Torin 1 inhibits both mTORC1/2 complexes with IC50 values between 2 and 10 nM. Torin 1 is an effective inducer of autophagy.
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Torin 1 | 99.28% | Torin 1 is a potent inhibitor of mTOR with an IC50 of 3 nM. Torin 1 inhibits both mTORC1/2 complexes with IC50 values between 2 and 10 nM. Torin 1 is an effective inducer of autophagy. | ||||||||||||||||||||
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Torin 1 (Standard) | ≥98% | Torin 1 (Standard) is the analytical standard of Torin 1 (HY-13003). This product is intended for research and analytical applications. Torin 1 is a potent inhibitor of mTOR with an IC50 of 3 nM. Torin 1 inhibits both mTORC1/2 complexes with IC50 values between 2 and 10 nM. Torin 1 is an effective inducer of autophagy. | ||||||||||||||||||||
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