1. Signaling Pathways
  2. Epigenetics
    TGF-beta/Smad
  3. PKC
  4. PKCθ Inhibitors

PKCθ Inhibitors

PKC

PKCα

PKCβ

PKCγ

PKCδ

PKCε

PKCη

PKCζ

PKCθ

PKCμ

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform PKCθ together.

Please try each isoform separately.

PKCθ Specific Inhibitors
Product Name PKCθ PKCα PKCβ PKCδ PKCε PKCη PKCθ Selectivity Purity
VTX-27
PKCθ, Ki: 0.08 nM
PKCα, Ki: 356 nM
 
PKCδ, Ki: 16 nM
    Selective Inhibitor 99.64%
Sotrastaurin
PKCθ, Ki: 0.22 nM
PKCα, Ki: 0.95 nM
PKCβI, Ki: 0.64 nM
PKCδ, Ki: 2.1 nM
PKCε, Ki: 3.2 nM
PKCη, Ki: 1.8 nM
Pan Inhibitor 99.83%
Afuresertib
PKCθ, IC50: 510 nM
 
PKC-βI, IC50: 430 nM
   
PKCη, IC50: 210 nM
Pan Inhibitor 99.23%
LXS196
PKCθ, IC50: 0.4 nM
PKCα, IC50: 1.9 nM
        Pan Inhibitor 99.68%
Afuresertib hydrochloride
PKCθ, IC50: 510 nM
 
PKC-βI, IC50: 430 nM
   
PKCη, IC50: 210 nM
Pan Inhibitor 98.02%
PKC-theta inhibitor
PKCθ, IC50: 12 nM
          Pan Inhibitor 99.91%
TCS 21311
PKCθ, IC50: 68 nM
PKCα, IC50: 13 nM
        Pan Inhibitor >98.0%