1. Signaling Pathways
  2. PI3K/Akt/mTOR
    Stem Cell/Wnt
  3. GSK-3
  4. GSK-3β Inhibitors

GSK-3β Inhibitors

GSK-3

GSK-3α

GSK-3β

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Sorry. There is currently no product that acts on isoform GSK-3β together.

Please try each isoform separately.

GSK-3β Specific Inhibitors
Product Name GSK-3β GSK-3α GSK-3β Selectivity Purity
TWS119
GSK-3β, IC50: 30 nM
  Selective Inhibitor >98.0%
EHT 5372
GSK3β, IC50: 221 nM
GSK3α, IC50: 7.44 nM
Selective Inhibitor 98.07%
Tideglusib
GSK-3β(WT), IC50: 5 nM
GSK-3β(C199A), IC50: 60 nM
  Selective Inhibitor 99.66%
AR-A014418
GSK-3β, IC50: 104 nM
  Selective Inhibitor 97.22%
Cromolyn sodium
GSK-3β, IC50: 2 μM
  Selective Inhibitor 99.97%
TDZD-8
GSK-3β, IC50: 2 μM
  Selective Inhibitor 98.74%
Indirubin-3'-monoxime
GSK-3β, IC50: 22 nM
  Selective Inhibitor 99.95%
IM-12
GSK-3β, IC50: 53 nM
  Selective Inhibitor 96.45%
SB 415286
hGSK-3β, IC50: 77.5 nM
hGSK-3α, IC50: 77.5 nM
Selective Inhibitor 99.88%
CP21R7
GSK-3β, IC50: 1.8 nM
  Selective Inhibitor 99.77%
1-Azakenpaullone
GSK-3β, IC50: 18 nM
  Selective Inhibitor 98.20%
5-Iodo-indirubin-3'-monoxime
GSK-3β, IC50: 9 nM
  Selective Inhibitor
GNF4877
GSK3β, IC50: 16 nM
  Selective Inhibitor 98.85%
GSK-3β inhibitor 2
GSK-3β, IC50: 1.1 nM
  Selective Inhibitor
GSK-3β inhibitor 1
GSK-3β, IC50: 4.9 nM
  Selective Inhibitor
Indirubin-3'-monoxime-5-sulphonic acid
GSK-3β, IC50: 80 nM
  Selective Inhibitor
CHIR-99021
GSK-3β, IC50: 6.7 nM
GSK-3α, IC50: 10 nM
Pan Inhibitor 99.76%
SB 216763
GSK-3β, IC50: 34.3 nM
GSK-3α, IC50: 34.3 nM
Pan Inhibitor 98.01%
LY2090314
GSK-3β, IC50: 0.9 nM
GSK-3α, IC50: 1.5 nM
Pan Inhibitor 99.75%
BRD0705
GSK-3β(WT), IC50: 515 nM
GSK3α, IC50: 66 nM
GSK3α, Kd: 4.8 μM
Pan Inhibitor
GSK 3 Inhibitor IX
GSK-3β, IC50: 5 nM
GSK-3α, IC50: 5 nM
Pan Inhibitor 99.66%
CHIR-99021 trihydrochloride
GSK-3β, IC50: 6.7 nM
GSK-3α, IC50: 10 nM
Pan Inhibitor 97.93%
AZD1080
GSK-3β, pKi: 7.5
GSK-3α, pKi: 8.2
Pan Inhibitor 99.10%
CHIR-99021 monohydrochloride
GSK-3β, IC50: 6.7 nM
GSK-3α, IC50: 10 nM
Pan Inhibitor 99.93%
AZD2858
GSK-3β, IC50: 5 nM
GSK-3α, IC50: 0.9 nM
Pan Inhibitor 99.24%
CHIR-98014
GSK-3β, IC50: 0.58 nM
GSK-3α, IC50: 0.65 nM
Pan Inhibitor >98.0%
BIO-acetoxime
GSK-3β, IC50: 10 nM
GSK-3α, IC50: 10 nM
Pan Inhibitor >98.0%
Alsterpaullone
GSK-3β, IC50: 4 nM
GSK-3α, IC50: 4
Pan Inhibitor 97.30%
A 1070722
GSK-3β, Ki: 0.6 nM
GSK-3α, Ki: 0.6 nM
Pan Inhibitor >99.0%
TCS 21311
GSK-3β, IC50: 3 nM
  Pan Inhibitor >98.0%
9-ING-41
GSK-3β
  default Inhibitor