667463-62-9
667463-62-9
Chemical Structure
GSK 3 Inhibitor IX
Synonym(s): 6-Bromoindirubin-3'-oxime; BIO; MLS 2052
- CAS No.: 667463-62-9
- Formula:C16H10BrN3O2
- Molecular Weight:356.17
IUPAC Name: (2Z,3E)-6'-bromo-3-(hydroxyimino)-[2,3'-biindolinylidene]-2'-one
InChIKey: DDLZLOKCJHBUHD-WAVHTBQISA-N
SMILES: O/N=C(C1=CC=CC=C1N2)/C2=C3C(NC4=C/3C=CC(Br)=C4)=O
Biological Activity: GSK 3 Inhibitor IX (6-Bromoindirubin-3'-oxime; BIO) is a potent, selective, reversible and ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex with IC50s of 5 nM/320 nM/80 nM for (GSK-3α/β)/CDK1/CDK5, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GSK 3 Inhibitor IX | 99.47% | GSK 3 Inhibitor IX (6-Bromoindirubin-3'-oxime; BIO) is a potent, selective, reversible and ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex with IC50s of 5 nM/320 nM/80 nM for (GSK-3α/β)/CDK1/CDK5, respectively. | ||||||||||||||||||||
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GSK 3 Inhibitor IX (Standard) | ≥98% | GSK 3 Inhibitor IX (Standard) is the analytical standard of GSK 3 Inhibitor IX (HY-10580). This product is intended for research and analytical applications. GSK 3 Inhibitor IX (6-Bromoindirubin-3'-oxime; BIO) is a potent, selective, reversible and ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex with IC50s of 5 nM/320 nM/80 nM for (GSK-3α/β)/CDK1/CDK5, respectively. | ||||||||||||||||||||
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