MeBIO (Standard)
MeBIO (Standard) is the analytical standard of MeBIO (HY-103221). This product is intended for research and analytical applications. MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist, with IC50 of 44 μM (GSK-3) and 55 μM (CDK1/cyclin B), respectively.
For research use only. We do not sell to patients.
- CAS No.: 667463-95-8
- Formula: C17H12BrN3O2
- Molecular Weight:370.20
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 667463-95-8
-
Molecular Weight 370.20
-
Formula C17H12BrN3O2
-
SMILES
O=C1N(C)C2=C(C=CC(Br)=C2)/C1=C3NC4=C(C=CC=C4)C/3=N\O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Meijer L, et al. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem Biol. 2003 Dec;10(12):1255-66. [Content Brief]
[2]. Knockaert, et al. Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins. Oncogene 23.25 (2004): 4400-4412. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)