1. Signaling Pathways
  2. PI3K/Akt/mTOR
    Stem Cell/Wnt
  3. GSK-3
  4. GSK-3α Inhibitors

GSK-3α Inhibitors

GSK-3

GSK-3α

GSK-3β

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Sorry. There is currently no product that acts on isoform GSK-3α together.

Please try each isoform separately.

GSK-3α Specific Inhibitors
Product Name GSK-3α GSK-3β GSK-3α Selectivity Purity
EHT 5372
GSK3α, IC50: 7.44 nM
GSK3β, IC50: 221 nM
Selective Inhibitor 98.07%
BRD0705
GSK3α, IC50: 66 nM
GSK3α, Kd: 4.8 μM
GSK-3β(WT), IC50: 515 nM
Selective Inhibitor
SB 415286
hGSK-3α, IC50: 77.5 nM
hGSK-3β, IC50: 77.5 nM
Selective Inhibitor 99.88%
CHIR-99021
GSK-3α, IC50: 10 nM
GSK-3β, IC50: 6.7 nM
Pan Inhibitor 99.76%
SB 216763
GSK-3α, IC50: 34.3 nM
GSK-3β, IC50: 34.3 nM
Pan Inhibitor 98.01%
LY2090314
GSK-3α, IC50: 1.5 nM
GSK-3β, IC50: 0.9 nM
Pan Inhibitor 99.75%
GSK 3 Inhibitor IX
GSK-3α, IC50: 5 nM
GSK-3β, IC50: 5 nM
Pan Inhibitor 99.66%
CHIR-99021 trihydrochloride
GSK-3α, IC50: 10 nM
GSK-3β, IC50: 6.7 nM
Pan Inhibitor 97.93%
AZD1080
GSK-3α, pKi: 8.2
GSK-3β, pKi: 7.5
Pan Inhibitor 99.10%
CHIR-99021 monohydrochloride
GSK-3α, IC50: 10 nM
GSK-3β, IC50: 6.7 nM
Pan Inhibitor 99.93%
AZD2858
GSK-3α, IC50: 0.9 nM
GSK-3β, IC50: 5 nM
Pan Inhibitor 99.24%
CHIR-98014
GSK-3α, IC50: 0.65 nM
GSK-3β, IC50: 0.58 nM
Pan Inhibitor >98.0%
BIO-acetoxime
GSK-3α, IC50: 10 nM
GSK-3β, IC50: 10 nM
Pan Inhibitor >98.0%
Alsterpaullone
GSK-3α, IC50: 4
GSK-3β, IC50: 4 nM
Pan Inhibitor 97.30%
A 1070722
GSK-3α, Ki: 0.6 nM
GSK-3β, Ki: 0.6 nM
Pan Inhibitor >99.0%