252935-94-7

CHIR-98014 Chemical Structure
252935-94-7

Chemical Structure

CHIR-98014

  • CAS No.: 252935-94-7
  • Formula:C20H17Cl2N9O2
  • Molecular Weight:486.31

IUPAC Name: N2-(2-((4-(2,4-dichlorophenyl)-5-(1H-imidazol-1-yl)pyrimidin-2-yl)amino)ethyl)-5-nitropyridine-2,6-diamine

InChIKey: MDZCSIDIPDZWKL-UHFFFAOYSA-N

SMILES: ClC1=CC(Cl)=CC=C1C2=NC(NCCNC3=CC=C([N+]([O-])=O)C(N)=N3)=NC=C2N4C=CN=C4

Biological Activity: CHIR-98014 is a potent, cell-permeable GSK-3 inhibitor with IC50s of 0.65 and 0.58 nM for GSK-3α and GSK-3β, respectively; it shows less potent activities against cdc2 and erk2.

Cat. No. Product Name Purity Description Pricing
HY-13076 		CHIR-98014 98.44% CHIR-98014 is a potent, cell-permeable GSK-3 inhibitor with IC50s of 0.65 and 0.58 nM for GSK-3α and GSK-3β, respectively; it shows less potent activities against cdc2 and erk2.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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