1. PI3K/Akt/mTOR
    Stem Cell/Wnt
  2. GSK-3
  3. CHIR-98023

CHIR-98023 

Cat. No.: HY-126125
Handling Instructions

CHIR-98023 is a potent, selective and reversible inhibitor of GSK3, with IC50s of 10 nM and 6.7 nM for GSK3α and GSK3β, respectively. CHIR-98023 can improve insulin action and glucose metabolism.

For research use only. We do not sell to patients.

CHIR-98023 Chemical Structure

CHIR-98023 Chemical Structure

CAS No. : 252916-76-0

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Description

CHIR-98023 is a potent, selective and reversible inhibitor of GSK3, with IC50s of 10 nM and 6.7 nM for GSK3α and GSK3β, respectively. CHIR-98023 can improve insulin action and glucose metabolism[1][2].

IC50 & Target[1]

GSK3α

10 nM (IC50)

GSK3β

6.7 nM (IC50)

Molecular Weight

471.30

Formula

C20H16Cl2N8O2

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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CHIR-98023
Cat. No.:
HY-126125
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