1. Signaling Pathways
  2. PI3K/Akt/mTOR
    Stem Cell/Wnt
  3. GSK-3
  4. GSK-3 Isoform

GSK-3

 

GSK-3 Related Products (32):

Cat. No. Product Name Effect Purity
  • HY-12524
    Bikinin
    Inhibitor 99.96%
    Bikinin is a non-steroidal, ATP-competitive inhibitor of plant GSK-3/Shaggy-like kinases and activates BR (brassinosteroids) signaling.
  • HY-128879A
    VP3.15 dihydrobromide
    Inhibitor ≥98.0%
    VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively.
  • HY-103647
    K00546
    Inhibitor 98.78%
    K00546 is a potent CDK1 and CDK2 inhibitor with IC50s of 0.6 nM and 0.5 nM for CDK1/cyclin B and CDK2/cyclin A, respectively.
  • HY-13973A
    GSK-3 inhibitor 1
    Inhibitor 99.89%
    GSK-3 inhibitor 1 (compound core 3) is a GSK-3 inhibitor that induces stem/progenitor cell self-renewal (e.
  • HY-134622
    GSK-3/CDK5/CDK2-IN-1
    Inhibitor 98.56%
    GSK-3/CDK5/CDK2-IN-1, an imidazole derivative, is an inhibitor of cdk5, cdk2, and GSK-3 extracted from patent WO2002010141A1, example 9a.
  • HY-103221
    MeBIO
    Inhibitor ≥98.0%
    MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist, with IC50 of 44 μM (GSK-3) and 55 μM (CDK1/cyclin B), respectively.
  • HY-P1113A
    Phospho-Glycogen Synthase Peptide-2(substrate) TFA
    98.02%
    Phospho-Glycogen Synthase Peptide-2 (substrate) is peptide substrate for glycogen synthase kinase-3 (GSK-3) and can be used for affinity purification of protein-serine kinases.
  • HY-Q48328
    GSK3-IN-1
    Inhibitor 99.86%
    GSK3-IN-1 (compound 11) is a GSK-3 inhibitor with an IC50 value of 12 μM.
  • HY-126144A
    (E/Z)-GSK-3β inhibitor 1
    Inhibitor 98.56%
    (E/Z)-GSK-3β inhibitor 1 is a racemic compound of (E)-GSK-3β inhibitor 1 and (Z)-GSK-3β inhibitor 1 isomers.
  • HY-116830B
    BRD5648
    BRD5648 ((R)-BRD0705) is a negative control of BRD0705.
  • HY-128879
    VP3.15
    Inhibitor
    VP3.15 is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively.
  • HY-144290
    ARN25068
    Inhibitor
    ARN25068 is a sub-micromolar inhibitor of the three protein kinases, GSK-3β, FYN and DYRK1A to tackle tau hyperphosphorylation.
  • HY-107815
    CHIR 98024
    Inhibitor
    CHIR 98024 (Compound L) is a glycogen synthase kinase 3 (GSK3) inhibitor with an EC50 of 0.2566 μM.
  • HY-P1113
    Phospho-Glycogen Synthase Peptide-2(substrate)
    Phospho-Glycogen Synthase Peptide-2 (substrate) is peptide substrate for glycogen synthase kinase-3 (GSK-3) and can be used for affinity purification of protein-serine kinases.
  • HY-112336
    Aloisine RP106
    Inhibitor
    Aloisine RP106 (compound 38) is a potent inhibitor of Cdk1/cyclin B, Cdk5/p25, and GSK3 with IC50s of 0.70µM, 1.5µM, 0.92 µM, respectively.
  • HY-10096
    TCS2002
    Inhibitor
    TCS2002 (Compound 9b) is a highly selective, orally bioavailable and potent GSK-3β inhibitor with the IC50 of 35 nM.
  • HY-14872S1
    Tideglusib-d7-1
    Inhibitor
  • HY-148133
    GSK-3β inhibitor 12
    Inhibitor
    GSK-3β inhibitor 12 (compound 15) is an inhibitor of GSK-3β.
  • HY-10512S
    AR-A014418-d3
    Inhibitor
    AR-A014418-d3 (AR 0133418-d3) is the deuterium labeled AR-A014418.
  • HY-107530
    3F8
    Inhibitor
    3F8 is a potent and selective GSK-3β inhibitor that could be useful as new reagent and potential therapeutic candidate for GSK3 related diseases.