1. Cell Cycle/DNA Damage
    Stem Cell/Wnt
    PI3K/Akt/mTOR
  2. CDK
    GSK-3
  3. GSK-3/CDK5/CDK2-IN-1

GSK-3/CDK5/CDK2-IN-1 

Cat. No.: HY-134622
Handling Instructions

GSK-3/CDK5/CDK2-IN-1, an imidazole derivative, is an inhibitor of cdk5, cdk2, and GSK-3 extracted from patent WO2002010141A1, example 9a. GSK-3/CDK5/CDK2-IN-1 can be used for the research of cancer, and neurodegenerative diseases.

For research use only. We do not sell to patients.

GSK-3/CDK5/CDK2-IN-1 Chemical Structure

GSK-3/CDK5/CDK2-IN-1 Chemical Structure

CAS No. : 395074-72-3

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Description

GSK-3/CDK5/CDK2-IN-1, an imidazole derivative, is an inhibitor of cdk5, cdk2, and GSK-3 extracted from patent WO2002010141A1, example 9a. GSK-3/CDK5/CDK2-IN-1 can be used for the research of cancer, and neurodegenerative diseases[1].

IC50 & Target

cdk5[1]
cdk2[1]
GSK-3[1]

In Vitro

GSK-3/CDK5/CDK2-IN-1 inhibits the phosphorylation of cdk5 peptide substrate phosphorylation, with an IC50 of less than about 50 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

362.42

Formula

C₂₁H₂₂N₄O₂

CAS No.
SMILES

O=C(NC1=CN([[email protected]]2C[[email protected]@H](NC(C)=O)C2)C=N1)CC3=CC=C4C=CC=CC4=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

GSK-3/CDK5/CDK2-IN-1CDKGSK-3Cyclin dependent kinaseGlycogen synthase kinase-3Glycogen synthase kinase 3imidazolecdk5cdk2cancerneurodegenerativeInhibitorinhibitorinhibit

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GSK-3/CDK5/CDK2-IN-1
Cat. No.:
HY-134622
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