1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. CDK
  4. CDK8 Inhibitors

CDK8 Inhibitors

CDK1

CDK2

CDK3

CDK4

CDK5

CDK6

CDK7

CDK8

CDK9

CDK11

CDK12

CDK13

CDK14

CDK16

CDK19

CDC

CLK

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform CDK8 together.

Please try each isoform separately.

CDK8 Specific Inhibitors
Product Name CDK8 CDK1 CDK2 CDK5 CDK7 CDK9 CDK19 CDK8 Selectivity Purity
MSC2530818
CDK8, IC50: 2.6 nM
            Selective Inhibitor 99.69%
AS2863619
CDK8, IC50: 0.61 nM
         
CDK19, IC50: 4.28 nM
Selective Inhibitor >98.0%
BI-1347
CDK8, IC50: 1.1 nM
            Selective Inhibitor 99.83%
JH-XI-10-02
CDK8, IC50: 159 nM
            Selective Inhibitor 97.28%
AS2863619 free base
CDK8, IC50: 0.61 nM
         
CDK19, IC50: 4.28 nM
Selective Inhibitor >98.0%
BRD6989
CDK8, IC50: ~200 nM
recombinant CDK8, IC50: ~0.5 μM
         
recombinant CDK19, IC50: >30 μM
Selective Inhibitor
CCT-251921
CDK8, IC50: 2.3 nM
         
CDK19, IC50: 2.6 nM
Pan Inhibitor 98.70%
Senexin A
CDK8, Kd: 0.83 μM
         
CDK19, Kd: 0.31 μM
Pan Inhibitor 99.94%
Wogonin
CDK8
            Pan Inhibitor 99.98%
THZ2
CDK8, IC50: 6830 nM
CDK1, IC50: 96.9 nM
CDK2, IC50: 222 nM
CDK5, IC50: 134 nM
CDK7, IC50: 13.9 nM
CDK9, IC50: 194 nM
  Pan Inhibitor 99.03%
SEL120-34A monohydrochloride
CDK8/CycC, IC50: 4.4 nM
       
CDK9/cycT, IC50: 1070 nM
CDK19/CycC, IC50: 10.4 nM
Pan Inhibitor 99.98%
LY2857785
CDK8, IC50: 0.016 μM
     
CDK7, IC50: 0.246 μM
CDK9, IC50: 0.011 μM
  Pan Inhibitor 98.88%
SEL120-34A HCl
CDK8/CycC, IC50: 4.4 nM
       
CDK9/cycT, IC50: 1070 nM
CDK19/CycC, IC50: 10.4 nM
Pan Inhibitor 99.80%
CDK8-IN-1
CDK8, IC50: 3 nM
            Pan Inhibitor 98.62%
SEL120-34A
CDK8/CycC, IC50: 4.4 nM
       
CDK9/cycT, IC50: 1070 nM
CDK19/CycC, IC50: 10.4 nM
Pan Inhibitor
CDK8/19-IN-1
CDK8/CycC, IC50: 0.46 nM
       
CDK9, IC50: 270 nM
CDK19/CycC, IC50: 0.99 nM
Pan Inhibitor