2163056-91-3
2163056-91-3
Chemical Structure
BI-1347
- CAS No.: 2163056-91-3
- Formula:C22H20N4O
- Molecular Weight:356.42
IUPAC Name: 2-(4-(4-(isoquinolin-4-yl)phenyl)-1H-pyrazol-1-yl)-N,N-dimethylacetamide
InChIKey: WULUGQONDYDNKY-UHFFFAOYSA-N
SMILES: O=C(N(C)C)CN1N=CC(C2=CC=C(C3=CN=CC4=C3C=CC=C4)C=C2)=C1
Biological Activity: BI-1347 is an orally active, selective and potent CDK8 inhibitor (IC50=1.1 nM). BI-1347 shows anti-tumoral activity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BI-1347 | 99.85% | BI-1347 is an orally active, selective and potent CDK8 inhibitor (IC50=1.1 nM). BI-1347 shows anti-tumoral activity. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.79
HY-168683CDK8 ligand 1 -
Similarity Score 0.64
HY-149209LL-K8-22 -
Similarity Score 0.52
HY-153531TM-04-176-01 -
Similarity Score 0.51
![3',5'-Di(pyridin-3-yl)-[1,1'-biphenyl]-4-carboxylic acid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w1049757.gif)
HY-W10497573',5'-Di(pyridin-3-yl)-[1,1'-biphenyl]-4-carboxylic acid -
Similarity Score 0.51
HY-W10498024,4'-(Quinoline-5,8-diyl)dibenzoic acid -
Similarity Score 0.51
HY-179400LDN-193688 -
Similarity Score 0.50
HY-W1121714,4'-Pyridine-3,5-diyldibenzoicacid -
Similarity Score 0.50
HY-W1127401,4-Di(pyridin-4-yl)naphthalene -
Similarity Score 0.50
HY-W1129814,4'-Di(1H-pyrazol-4-yl)-1,1'-biphenyl -
Explore the MedChemAI to find more analogs
![3',5'-Di(pyridin-3-yl)-[1,1'-biphenyl]-4-carboxylic acid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w1049757.gif)
