1449228-40-3
1449228-40-3
Chemical Structure
Senexin B
Synonym(s): SNX2-1-165; BCD-115
- CAS 番号: 1449228-40-3
- Formula:C27H26N6O
- Molecular Weight:450.53
IUPAC Name: 4-((2-(6-(4-methylpiperazine-1-carbonyl)naphthalen-2-yl)ethyl)amino)quinazoline-6-carbonitrile
InChIKey: VNADJTWHOAMTLY-UHFFFAOYSA-N
SMILES: N#CC1=CC2=C(NCCC3=CC=C4C=C(C(N5CCN(C)CC5)=O)C=CC4=C3)N=CN=C2C=C1
Biological Activity: Senexin B (SNX2-1-165; BCD-115) is a potent, highly water-soluble and bioavailable CDK8/19 inhibitor, with Kds of 140 nM for CDK8 and 80 nM for CDK19.
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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Senexin B | 99.09% | Senexin B (SNX2-1-165; BCD-115) is a potent, highly water-soluble and bioavailable CDK8/19 inhibitor, with Kds of 140 nM for CDK8 and 80 nM for CDK19. | ||||||||||||||||||||
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Senexin B (Standard) | ≥98% | Senexin B (Standard) (SNX2-1-165 (Standard)) is the analytical standard of Senexin B (HY-101800). This product is intended for research and analytical applications. Senexin B (SNX2-1-165; BCD-115) is a potent, highly water-soluble and bioavailable CDK8/19 inhibitor, with Kds of 140 nM for CDK8 and 80 nM for CDK19. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.81
HY-143889Senexin C -
Similarity Score 0.71
HY-117988SNX2-1-108 -
Similarity Score 0.62
HY-15681ASenexin A hydrochloride -
Similarity Score 0.62
HY-15681Senexin A -
Similarity Score 0.54
HY-13812RQNZ (Standard) -
Similarity Score 0.49
HY-101922RIRAK4-IN-1 (Standard) -
Similarity Score 0.49
HY-126020Bractoppin -
Similarity Score 0.49
HY-127179ML189 -
Similarity Score 0.49
HY-15182Collagen proline hydroxylase inhibitor-1 -
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