2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. HSP
  4. ML189

ML189 is an HSP90 inhibitor. ML189 can be used in the research of infectious diseases such as candidiasis.

For research use only. We do not sell to patients.

ML189

ML189 Chemical Structure

CAS No. : 337328-21-9

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ML189 Related Antibodies

Top Publications Citing Use of Products

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HSP40 HSP70 HSP90 HSP105 HSF1 HSP HSPA5

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Description

ML189 is an HSP90 inhibitor. ML189 can be used in the research of infectious diseases such as candidiasis[1][2].

IC50 & Target[1]

HSP90

 

Cellular Effect
Cell Line Type Value Description References
NIH3T3 IC50
21 μM
Compound: 1, ML189
Cytotoxicity in mouse NIH/3T3 cells after 48 hrs by Almar blue fluorimetry
Cytotoxicity in mouse NIH/3T3 cells after 48 hrs by Almar blue fluorimetry
[PMID: 21802942]
Molecular Weight

386.27

Formula

C20H17Cl2N3O
CAS No.
SMILES

O=C(C1=CC=C(Cl)C=C1)N2CCN(C3=CC=NC4=CC(Cl)=CC=C34)CC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ML189 Related Classifications

  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ML189337328-21-9ML 189ML-189HSPHeat shock proteinsHSP90infectious diseasesInhibitorinhibitorinhibit

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