ML189
ML189 is an HSP90 inhibitor. ML189 can be used in the research of infectious diseases such as candidiasis.
For research use only. We do not sell to patients.
- CAS No.: 337328-21-9
- Formula: C20H17Cl2N3O
- Molecular Weight:386.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
HSP90 |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| NIH3T3 | IC50 |
21 μM
Compound: 1, ML189
|
Cytotoxicity in mouse NIH/3T3 cells after 48 hrs by Almar blue fluorimetry
Cytotoxicity in mouse NIH/3T3 cells after 48 hrs by Almar blue fluorimetry
|
[PMID: 21802942] |
Chemical Information
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CAS No. 337328-21-9
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Molecular Weight 386.27
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Formula C20H17Cl2N3O
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SMILES
O=C(C1=CC=C(Cl)C=C1)N2CCN(C3=CC=NC4=CC(Cl)=CC=C34)CC2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hartland CL, et al. Identification of small molecules that selectively inhibit fluconazole-resistant Candida albicans in the presence of fluconazole but not in its absence. 2010 Oct 29. [Content Brief]
[2]. Tian J, et al. Overcoming matrix effects: GC method development for the determination of triethylamine and dimethyl sulfoxide in a drug substance. J Chromatogr Sci. 2014 Jan;52(1):36-41. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)