337328-21-9
337328-21-9
Chemical Structure
ML189
- CAS No.: 337328-21-9
- Formula:C20H17Cl2N3O
- Molecular Weight:386.27
IUPAC Name: (4-chlorophenyl)(4-(7-chloroquinolin-4-yl)piperazin-1-yl)methanone
InChIKey: AAYTXOPXLXAKHP-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(Cl)C=C1)N2CCN(C3=CC=NC4=CC(Cl)=CC=C34)CC2
Biological Activity: ML189 is an HSP90 inhibitor. ML189 can be used in the research of infectious diseases such as candidiasis[1][2].
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ML189 | ML189 is an HSP90 inhibitor. ML189 can be used in the research of infectious diseases such as candidiasis. | |||||||||||||||||||||
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References
- [1]. Hartland CL, et al. Identification of small molecules that selectively inhibit fluconazole-resistant Candida albicans in the presence of fluconazole but not in its absence. 2010 Oct 29. [Content Brief]
- [2]. Tian J, et al. Overcoming matrix effects: GC method development for the determination of triethylamine and dimethyl sulfoxide in a drug substance. J Chromatogr Sci. 2014 Jan;52(1):36-41. [Content Brief]
