1609452-30-3
Chemical Structure
Romaciclib hydrochloride
Synonym(s): SEL120-34A hydrochloride
- CAS No.: 1609452-30-3
- Formula:C15H18Br2N4.xHCl
- Molecular Weight:N/A
SMILES: CC1=C(Br)C(Br)=C2C3=C1N=C(N4CCNCC4)N3CCC2.Cl
Biological Activity: SEL120-34A hydrochloride is a potent, selective, orally available, ATP-competitive CDK8 inhibitor, with IC50s of 4.4 nM and 10.4 nM for CDK8/CycC and CDK19/CycC, respectively, with antitumor activity.
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Romaciclib hydrochloride | 98.82% | SEL120-34A hydrochloride is a potent, selective, orally available, ATP-competitive CDK8 inhibitor, with IC50s of 4.4 nM and 10.4 nM for CDK8/CycC and CDK19/CycC, respectively, with antitumor activity. | ||||||||||||||||||||
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Similarity Score 1.00
HY-111388ARomaciclib monohydrochloride -
Similarity Score 0.98
HY-111388SEL120-34A -
Similarity Score 0.55
HY-158377CDK8/19-IN-2 -
Similarity Score 0.48
HY-108633BYK 49187 -
Similarity Score 0.46
HY-113669A-940894 -
Similarity Score 0.42
HY-B1210Pipemidic acid -
Similarity Score 0.42
HY-105090Lerisetron -
Similarity Score 0.42
HY-118282mPGES1-IN-7 -
Similarity Score 0.41
HY-Z7642Ciprofloxacin impurity 7 -
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