CDK5

CDK5 Related Products (65)
Recombinant Proteins (1)

By Type:	Pan (57) Selective (8)

Cat. No.	Product Name	Effect	Purity

HY-16297A

Abemaciclib	Inhibitor	99.83%
Abemaciclib (LY2835219) is a selective CDK4/6 inhibitor with IC₅₀ values of 2 nM and 10 nM for CDK4 and CDK6, respectively.

HY-10492

Dinaciclib	Inhibitor	99.44%
Dinaciclib (SCH 727965) is a potent inhibitor of CDK, with IC₅₀s of 1 nM, 1 nM, 3 nM, and 4 nM for CDK2, CDK5, CDK1, and CDK9, respectively.

HY-30237

Seliciclib	Inhibitor	98.73%
Seliciclib (Roscovitine) is an orally bioavailable and selective CDKs inhibitor with IC₅₀s of 0.2 μM, 0.65 μM, and 0.7 μM for CDK5, Cdc2, and CDK2, respectively.

HY-16297

Abemaciclib methanesulfonate	Inhibitor	99.68%
Abemaciclib methanesulfonate (LY2835219 methanesulfonate) is a selective CDK4/6 inhibitor with IC₅₀s of 2 nM and 10 nM for CDK4 and CDK6, respectively.

HY-12302

Kenpaullone	Inhibitor	98.01%
Kenpaullone is a potent inhibitor of CDK1/cyclin B and GSK-3β, with IC₅₀s of 0.4 μM and 23 nM, and also inhibits CDK2/cyclin A, CDK2/cyclin E, and CDK5/p25 with IC₅₀s of 0.68 μM, 7.5 μM, 0.85 μM, respectively.

HY-151409

CDK1-IN-5	Inhibitor
CDK1-IN-5 (10h) is a selective CDK1 inhibitor with IC₅₀s of 42.19, 188.71 and 354.15 nM for CDK1, CDK2 and CDK5, respectively.

HY-151407

CDK1-IN-3	Inhibitor
CDK1-IN-3 (8g) is a selective CDK1 inhibitor with IC₅₀s of 36.8, 305.17 and 369.37 nM for CDK1, CDK2 and CDK5, respectively.

HY-151878

CDK7-IN-20

Inhibitor

CDK7-IN-20 is a potent, selective and irreversible CDK7 (HY-50940

AT7519

Inhibitor 99.76%

AT7519 (AT7519M) as a potent inhibitor of CDKs, with IC₅₀s of 210, 47, 100, 13, 170, and <10 nM for CDK1, CDK2, CDK4 to CDK6, and CDK9, respectively.

HY-10580

GSK 3 Inhibitor IX

Inhibitor 99.74%

GSK 3 Inhibitor IX (6-Bromoindirubin-3'-oxime; BIO) is a potent, selective, reversible and ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex with IC₅₀s of 5 nM/320 nM/80 nM for (GSK-3α/β)/CDK1/CDK5, respectively.

HY-15154

NG 52

Inhibitor 99.97%

NG 52 is a potent, cell-permeable, selective, ATP-compatible and orally active Cdc28p and Pho85p kinase inhibitor with IC₅₀s of 7 μM and 2 μM, respectively.

HY-10012

AZD-5438

Inhibitor 99.85%

AZD-5438 is a potent CDK1, CDK2, and CDK9 inhibitor, with IC₅₀s of 16 nM, 6 nM, and 20 nM in cell-free assays, respectively.

HY-103712A

Samuraciclib hydrochloride

Inhibitor 99.98%

Samuraciclib hydrochloride (CT7001 hydrochloride) is a potent, selective, ATP-competitive and orally active CDK7 inhibitor, with an IC₅₀ of 41 nM.

HY-11009

CGP60474

Inhibitor 98.70%

CGP60474, a highly potent anti-endotoxemic agent, is a potent cyclin-dependent kinase (CDK) inhibitor (IC₅₀ values are 26, 3, 4, 216, 10, 200 and 13 nM for CDK1/B, CDK2/E, CDK2/A, CDK4/D, CDK5/p25, CDK7/H and CDK9/T, respectively).

HY-10014

R547

Inhibitor 99.57%

R547 is a potent, selective and orally active ATP-competitive CDK inhibitor, with K_is of 2 nM, 3 nM and 1 nM for CDK1/cyclin B, CDK2/cyclin E and CDK4/cyclin D1, respectively.

HY-18340A

(R)-CR8 trihydrochloride

Inhibitor 99.02%

(R)-CR8 (CR8) trihydrochloride, a second-generation analog of Roscovitine, is a potent CDK1/2/5/7/9 inhibitor.

HY-123772

CDK5 inhibitor 20-223

Inhibitor 99.64%

CDK5 inhibitor 20-223 is a potent CDK2 and CDK5 inhibitor with IC₅₀s of 6.0 and 8.8 nM, respectively.

HY-13461A

PHA-767491 hydrochloride

Inhibitor 98.06%

PHA-767491 hydrochloride is a dual Cdc7/Cdk9 inhibitor, with IC₅₀s of 10 nM and 34 nM, respectively.

HY-12871B

Atuveciclib

Inhibitor 99.20%

Atuveciclib (BAY-1143572) is a potent and highly selective, oral PTEFb/CDK9 inhibitor.

HY-103712B

Samuraciclib hydrochloride hydrate

Inhibitor 99.08%

Samuraciclib (CT7001) hydrochloride hydrate is a potent, selective, ATP-competitive and orally active CDK7 inhibitor, with an IC₅₀ of 41 nM.

Your Search Returned No Results.

Please try again later.

Cat. No. Product Name / Synonyms Species Source

[email protected]

609-228-6898

Find Your Local Distributor

MedChemExpress
Contact Us
About Us
Headquarters
Distributors
Statement on False Report
Careers
Customer Support
Technical Support
Service
Ordering Information
Easy Return
Shipping Rates & Policies
Intellectual Property Promise
Resources
Free Sample
Literature
Molarity Calculator
Dilution Calculator
Terms & Conditions
Reconstitution Calculator
Specific Active Calculator

Subscribe to our E-newsletter

Name

Email *

Sorry, but the email address you supplied was invalid.

Thanks, your subscription has been confirmed. You will hear from us soon.

Submission failed, please try again later.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.

Copyright © 2013-2023 MedChemExpress. All Rights Reserved.

Site Map Privacy Policy

Join with us

As the situation with COVID-19 continues to unfold in every community, MedChemExpress is responding to the uncertainty caused by this outbreak thoughtfully and cautiously. Your need for high quality reagent doesn't stop during difficult times, and neither do we. We're doing our best to keep everyone healthy and safe in the workplace while also avoiding the interruptions to our day-to-day operations. If you need to change the delivery plan for items ordered, please contact us via email [email protected]. Thank you for being a loyal MedChemExpress customer, we are here to assist you as needed.

CDK5

CDK5 Related Products (65)

Recombinant Proteins (1)

CDK5 Related Products (65):