186692-46-6
186692-46-6
Chemical Structure
(R)-Roscovitine
Synonym(s): Seliciclib; CYC202
- CAS No.: 186692-46-6
- Formula:C19H26N6O
- Molecular Weight:354.45
IUPAC Name: (R)-2-((6-(benzylamino)-9-isopropyl-9H-purin-2-yl)amino)butan-1-ol
InChIKey: BTIHMVBBUGXLCJ-OAHLLOKOSA-N
SMILES: OC[C@H](NC1=NC(NCC2=CC=CC=C2)=C3C(N(C=N3)C(C)C)=N1)CC
Biological Activity: (R)-Roscovitine (Seliciclib) is an orally bioavailable, selective and BBB-permeable CDKs inhibitor with IC50s of 0.2 μM, 0.65 μM, and 0.7 μM for CDK5, Cdc2, and CDK2, respectively.
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(R)-Roscovitine | 99.53% | (R)-Roscovitine (Seliciclib) is an orally bioavailable, selective and BBB-permeable CDKs inhibitor with IC50s of 0.2 μM, 0.65 μM, and 0.7 μM for CDK5, Cdc2, and CDK2, respectively. | ||||||||||||||||||||
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(R)-Roscovitine (Standard) | ≥98% | (R)-Roscovitine (Standard) is the analytical standard of (R)-Roscovitine (HY-30237). This product is intended for research and analytical applications. (R)-Roscovitine (Seliciclib) is an orally bioavailable, selective and BBB-permeable CDKs inhibitor with IC50s of 0.2 μM, 0.65 μM, and 0.7 μM for CDK5, Cdc2, and CDK2, respectively. | ||||||||||||||||||||
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(R)-Roscovitine-d7 | (R)-Roscovitine-d7 (Seliciclib-d7; CYC202-d7) is deuterium-labeled (R)-Roscovitine (HY-30237). | |||||||||||||||||||||
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