212844-53-6
212844-53-6
Chemical Structure
Purvalanol A
Synonym(s): NG-60
- CAS No.: 212844-53-6
- Formula:C19H25ClN6O
- Molecular Weight:388.89
IUPAC Name: (R)-2-((6-((3-chlorophenyl)amino)-9-isopropyl-9H-purin-2-yl)amino)-3-methylbutan-1-ol
InChIKey: PMXCMJLOPOFPBT-HNNXBMFYSA-N
SMILES: CC([C@@H](NC1=NC(NC2=CC=CC(Cl)=C2)=C3N=CN(C(C)C)C3=N1)CO)C
Biological Activity: Purvalanol A is a potent CDK inhibitor, which inhibits cdc2-cyclin B, cdk2-cyclin A, cdk2-cyclin E, cdk4-cyclin D1, and cdk5-p35 with IC50s of 4, 70, 35, 850, 75 nM, resepctively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Purvalanol A | 98.61% | Purvalanol A is a potent CDK inhibitor, which inhibits cdc2-cyclin B, cdk2-cyclin A, cdk2-cyclin E, cdk4-cyclin D1, and cdk5-p35 with IC50s of 4, 70, 35, 850, 75 nM, resepctively. | ||||||||||||||||||||
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Purvalanol A (Standard) | ≥98% | Purvalanol A (Standard) is the analytical standard of Purvalanol A. This product is intended for research and analytical applications. Purvalanol A is a potent CDK inhibitor, which inhibits cdc2-cyclin B, cdk2-cyclin A, cdk2-cyclin E, cdk4-cyclin D1, and cdk5-p35 with IC50s of 4, 70, 35, 850, 75 nM, resepctively. | ||||||||||||||||||||
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Keywords
