Protein kinase affinity probe 1
Protein kinase affinity probe 1 is a novel protein kinase affinity probe for the functional identification of protein kinases (PKs). Protein kinase affinity probe 1 is a modified Purvalanol B (HY-18299) probe with 50% beads loading (Compound S3).
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- CAS No.: 2098621-90-8
- Formule: C26H39ClN8O2
- Masse moléculaire:531.09
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Description
In Vitro
"S" indicates that the PKI (Purvalanol B) is sepharose-bound[1].In a series of pull-down experiments from the lysates of HeLa cells, the effects of 0.1, 0.5, 1, 2, 5, 10, 25, and 50% loadings of PK inhibitors is determined. Examine higher bead loadings (75 and 100%) are prevented due to lack of compound solubility and poor reproducibility of the synthesis outcomes. 50% loading is the highest feasible in this study[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2098621-90-8
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Masse moléculaire 531.09
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Formule C26H39ClN8O2
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SMILES
O=C(NCCCCCCN)C1=CC=C(NC2=C3N=CN(C(C)C)C3=NC(N[C@@H](CO)C(C)C)=N2)C=C1Cl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protein kinase affinity probe 1 Related Classifications
HY-136219 Related Classifications
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