779353-01-4
779353-01-4
Chemical Structure
Dinaciclib
Synonym(s): SCH 727965
- CAS No.: 779353-01-4
- Formula:C21H28N6O2
- Molecular Weight:396.49
IUPAC Name: (S)-3-(((3-ethyl-5-(2-(2-hydroxyethyl)piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7-yl)amino)methyl)pyridine 1-oxide
InChIKey: PIMQWRZWLQKKBJ-SFHVURJKSA-N
SMILES: OCC[C@H]1N(CCCC1)C2=NC3=C(C=NN3C(NCC4=C[N+]([O-])=CC=C4)=C2)CC
Biological Activity: Dinaciclib (SCH 727965) is a potent inhibitor of CDK, with IC50s of 1 nM, 1 nM, 3 nM, and 4 nM for CDK2, CDK5, CDK1, and CDK9, respectively[1].
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Dinaciclib | 99.80% | Dinaciclib (SCH 727965) is a potent inhibitor of CDK, with IC50s of 1 nM, 1 nM, 3 nM, and 4 nM for CDK2, CDK5, CDK1, and CDK9, respectively. | ||||||||||||||||||||
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Dinaciclib (Standard) | ≥98% | Dinaciclib (Standard) is the analytical standard of Dinaciclib (HY-10492). This product is intended for research and analytical applications. Dinaciclib (SCH 727965) is a potent inhibitor of CDK, with IC50s of 1 nM, 1 nM, 3 nM, and 4 nM for CDK2, CDK5, CDK1, and CDK9, respectively. | ||||||||||||||||||||
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References
Keywords
