1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. CDK
  4. CDK12 Inhibitors

CDK12 Inhibitors

CDK1

CDK2

CDK3

CDK4

CDK5

CDK6

CDK7

CDK8

CDK9

CDK11

CDK12

CDK13

CDK14

CDK16

CDK19

CDC

CLK

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform CDK12 together.

Please try each isoform separately.

CDK12 Specific Inhibitors
Product Name CDK12 CDK2 CDK7 CDK9 CDK13 CDK12 Selectivity Purity
CDK12-IN-3
CDK12, IC50: 491 nM
        Selective Inhibitor 98.22%
BSJ-4-116
CDK12, IC50: 6 nM
        Selective Inhibitor 99.62%
CDK12-IN-2
CDK12, IC50: 52 nM
CDK2, IC50: >100 μM
CDK7, IC50: >10 μM
CDK7, IC50: >10 μM
CDK9, IC50: 16 μM
  Selective Inhibitor
BSJ-01-175
CDK12
     
CDK13
Selective Inhibitor
CDK12-IN-5
CDK12, IC50: 23.9 nM
CDK2/cyclinE, IC50: 173 μM
 
CDK9/cyclinT1, IC50: 127 μM
  Selective Inhibitor
CDK12-IN-6
CDK12, IC50: 1.19 μM
CDK2/cyclinE, IC50: >20 μM
 
CDK9/cyclinT1, IC50: >20 μM
  Selective Inhibitor
CDK12-IN-4
CDK12, IC50: 0.641 μM
CDK2/cyclinE, IC50: >20 μM
 
CDK9/cyclinT1, IC50: >20 μM
  Selective Inhibitor
THZ531
CDK12, IC50: 158 nM
 
CDK7, IC50: 8.5 μM
CDK9, IC50: 10.5 μM
CDK13, IC50: 69 nM
Pan Inhibitor 99.86%
SR-4835
CDK12, IC50: 99 nM
CDK12, Kd: 98 nM
     
CDK13, Kd: 4.9 nM
Pan Inhibitor 99.64%
SY-5609
CDK12, Ki: 870 nM
CDK2, Ki: 2600 nM
CDK7, Kd: 0.065 nM
CDK9, Ki: 960 nM
  Pan Inhibitor 99.66%