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Results for "

insulin

" in MedChemExpress (MCE) Product Catalog:

379

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12

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115

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66

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13

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Recombinant Proteins Recommended:
Cat. No. Compare Product Name Species Source
  • HY-P73243
    Insulin Protein, Human (P.pastoris)
    Maximum Cited Publications
    9 Publications Verification

    insulin; INS; IDDM; ILPR; IRDN; MODY10

    Human P. pastoris
    Insulin is an important hormone in glucose regulation, reducing blood glucose concentrations by increasing cellular permeability to simple sugars, amino acids, and fatty acids. Its multiple effects include accelerating glycolysis, promoting pentose phosphate cycle, and promoting hepatic glycogen synthesis. Insulin Protein, Human (P.pastoris) is a recombinant protein dimer complex containing human-derived Insulin protein, expressed by P. pastoris , with tag free. Insulin Protein, Human (P.pastoris), has molecular weight of ~6 kDa.
  • HY-P701240

    insulin; INS; IDDM; ILPR; IRDN; MODY10

    Bovine P. pastoris
    Insulin Protein regulates glucose metabolism in the body. It binds to insulin receptors, activating signaling pathways that facilitate glucose uptake and storage. Insulin Protein also regulates lipid metabolism and protein synthesis. Understanding its functions is crucial for developing treatments for diabetes and metabolic disorders. Insulin Protein, Bovine is a recombinant protein dimer complex containing bovine-derived Insulin protein, expressed by P. pastoris, with tag free. Insulin Protein, Bovine, has molecular weight of ~6 kDa.
  • HY-P73873

    CD 220; HHF5; INSR; insulin R; insulin receptor; IR

    Human HEK293
    The insulin R/CD220 protein is a receptor tyrosine kinase that coordinates insulin action by phosphorylating substrates such as IRS and SHC upon insulin binding. Phosphorylated IRS activates PI3K-AKT/PKB to exert metabolic effects, and activates Ras-MAPK to promote growth and differentiation. Insulin R/CD220 Protein, Human (HEK293, His) is the recombinant human-derived Insulin R/CD220 protein, expressed by HEK293 , with C-His labeled tag. The total length of Insulin R/CD220 Protein, Human (HEK293, His) is 929 a.a., with molecular weight of 110-125 kDa.
  • HY-P73244

    CD 220; HHF5; INSR; insulin R; insulin receptor; IR

    Human Sf9 insect cells
    The insulin R/CD220 protein is a receptor tyrosine kinase that coordinates insulin action by phosphorylating substrates such as IRS and SHC upon insulin binding. Phosphorylated IRS activates PI3K-AKT/PKB to exert metabolic effects, and activates Ras-MAPK to promote growth and differentiation. Insulin R/CD220 Protein, Human (sf9, His-GST) is the recombinant human-derived Insulin R/CD220 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of Insulin R/CD220 Protein, Human (sf9, His-GST) is 394 a.a., with molecular weight of ~70 kDa.
  • HY-P77515

    CD 220; HHF5; INSR; insulin R; insulin receptor; IR

    Human HEK293
    The insulin R/CD220 protein is a receptor tyrosine kinase that coordinates insulin action by phosphorylating substrates such as IRS and SHC upon insulin binding. Phosphorylated IRS activates PI3K-AKT/PKB to exert metabolic effects, and activates Ras-MAPK to promote growth and differentiation. Insulin R/CD220 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived Insulin R/CD220 protein, expressed by HEK293 , with C-His labeled tag. The total length of Insulin R/CD220 Protein, Human (Biotinylated, HEK293, His) is 929 a.a., with molecular weight of ~107 KDa.
  • HY-P73873A

    CD 220; HHF5; INSR; insulin R; insulin receptor; IR

    Human HEK293
    The insulin R/CD220 protein is a receptor tyrosine kinase that coordinates insulin action by phosphorylating substrates such as IRS and SHC upon insulin binding. Phosphorylated IRS activates PI3K-AKT/PKB to exert metabolic effects, and activates Ras-MAPK to promote growth and differentiation. Insulin R/CD220 Protein, Human (HEK293, C-His) is the recombinant human-derived Insulin R/CD220 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of Insulin R/CD220 Protein, Human (HEK293, C-His) is 929 a.a., with molecular weight of ~130 kDa.
  • HY-P70176

    rHuinsulin-like 3/INSL3, His; insulin-like 3; Leydig insulin-like peptide; Relaxin-like factor; INSL3; RLF; RLNL

    Human HEK293
  • HY-P71805

    Ins1; Ins-1; insulin-1

    Mouse P. pastoris
    Insulin-1 is an important regulator of glucose and can effectively lower blood sugar by increasing cellular permeability to simple sugars, amino acids, and fatty acids. Its effects include accelerating glycolysis, promoting pentose phosphate cycle, and promoting hepatic glycogen synthesis. Insulin-1/Ins1 Protein, Mouse (P.pastoris, Myc, His) is the recombinant mouse-derived Insulin-1/Ins1 protein, expressed by P. pastoris , with C-Myc, N-6*His labeled tag. The total length of Insulin-1/Ins1 Protein, Mouse (P.pastoris, Myc, His) is 84 a.a., with molecular weight (affected by relative charge) of 29 KDa.
  • HY-P71805Y

    Ins1; Ins-1; insulin-1

    Mouse P. pastoris
    Insulin-1, a vital regulator of glucose, efficiently reduces blood glucose by enhancing cellular permeability to monosaccharides, amino acids, and fatty acids. Its actions span glycolysis acceleration, pentose phosphate cycle promotion, and liver glycogen synthesis facilitation. Structurally, Insulin-1 is a heterodimer with A and B chains linked by two disulfide bonds, emphasizing its pivotal role in coordinating metabolic processes crucial for glucose homeostasis. Insulin-1/Ins1 Protein, Mouse (P.pastoris, Myc, His, solution) is the recombinant mouse-derived Insulin-1/Ins1 protein, expressed by P. pastoris , with N-His, C-Myc labeled tag. The total length of Insulin-1/Ins1 Protein, Mouse (P.pastoris, Myc, His, solution) is 84 a.a., with molecular weight of ~25 kDa.
  • HY-P70833

    Early Placenta insulin-Like Peptide; EPIL; insulin-Like Peptide 4; Placentin; INSL4

    Human HEK293
    The INSL4 protein plays a potentially critical role in the regulation of trophoblast development and bone formation. The specific mechanism of trophoblast development deserves further study. INSL4 Protein, Human (HEK293, His) is the recombinant human-derived INSL4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of INSL4 Protein, Human (HEK293, His) is 114 a.a., with molecular weight of ~9.0 kDa.
  • HY-P70291

    rHuinsulin-degrading enzyme/IDE, His ; insulin-Degrading Enzyme; Abeta-Degrading Protease; insulin Protease; insulinase; Insulysin; IDE

    Human HEK293
    Insulin/IDE protein is the key to the decomposition of cellular peptides. It participates in the degradation of insulin, APP peptides, IAPP peptides, natriuretic peptides, glucagon, bradykinin, kinins and other peptides, and affects intercellular peptide signaling. Substrate binding induces conformational changes that promote degradation of larger substrates such as insulin. Insulysin/IDE Protein, Human (HEK293, His) is the recombinant human-derived Insulysin/IDE protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Insulysin/IDE Protein, Human (HEK293, His) is 978 a.a., with molecular weight of ~120.0 kDa.
  • HY-P76455

    insulin-like peptide INSL6; Relaxin/insulin-like factor 1; INSL6; RIF1

    Human HEK293
    The INSL6 protein plays a crucial role in sperm development and fertilization, highlighting its importance in male reproductive biology. Its potential function in promoting sperm development and successful fertilization emphasizes its importance in reproductive physiology. INSL6 Protein, Human (HEK293, His) is the recombinant human-derived INSL6 protein, expressed by HEK293 , with C-His labeled tag. The total length of INSL6 Protein, Human (HEK293, His) is 178 a.a., with molecular weight of ~22.1 KDa.
  • HY-P701241

    IGF1; IGF-1; insulin-like growth factor 1; insulin-like growth factor I; Somatomedin C; somatomedin-C

    Others E. coli
    IGF-I protein is similar to insulin and exerts effective growth-promoting activity as a ligand of IGF1R. Binding to the α subunit of IGF1R activates intrinsic tyrosine kinase, triggering autophosphorylation of the β subunit. IGF-I Protein, Salmon is the recombinant IGF-I protein, expressed by E. coli , with tag free. The total length of IGF-I Protein, Salmon is 70 a.a., with molecular weight of ~8 kDa.
  • HY-P700475

    insulin-like growth factor 2 (somatomedin A); INSIGF; pp9974; C11orf43; FLJ22066; FLJ44734; IGF2; insulin-like growth factor 2; IGF-II; somatomedin A; somatomedin-A; insulin-like growth factor II; insulin-like growth factor type 2; putative insulin-like growth factor II associated protein; chromosome 11 open reading frame 43; OTTHUMP00000011157; OTTHUMP00000011018

    Human E. coli
    The IGF2 protein is an important member of the insulin-like growth factor family and plays an important role in mammalian growth, fetoplacental development, and adult glucose metabolism. Regulated by placental prolactin, affecting tissue differentiation. IGF2 Protein, Human (GST) is the recombinant human-derived IGF2 protein, expressed by E. coli , with N-GST labeled tag. The total length of IGF2 Protein, Human (GST) is 151 a.a., with molecular weight of 44.1 kDa.
  • HY-P70698

    IGF1; IGF-1; insulin-like growth factor 1; insulin-like growth factor I; Somatomedin C; somatomedin-C

    Mouse E. coli
    IGF-I/IGF-1 Protein, Mouse (His) is a mitogenic cytokine, binds to IGF type 1 receptor, and modulates growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle, endothelium, and bone. IGF1 also mediates neuroprotective mechanism.
  • HY-P70698A

    IGF1; IGF-1; insulin-like growth factor 1; insulin-like growth factor I; Somatomedin C; somatomedin-C

    Mouse E. coli
    The IGF-I/IGF-1 protein is structurally similar to insulin and has potent growth-promoting activity. As a physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts, exceeding the efficacy of insulin at lower concentrations. IGF-I/IGF-1 Protein, Mouse (N-His) is the recombinant mouse-derived IGF-I/IGF-1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IGF-I/IGF-1 Protein, Mouse (N-His) is 70 a.a., with molecular weight of ~10 kDa.
  • HY-P702338

    insulin-induced gene 2 protein; INSIG-2

    Human E. coli Cell-free
    The INSIG2 protein is a key oxysterol-binding protein that regulates cholesterol synthesis by controlling SCAP transport and HMGCR degradation. As a negative regulator, INSIG2 retains the SCAP-SREBP complex in the endoplasmic reticulum (ER) and inhibits SREBP processing. INSIG2 Protein, Human (Cell-Free, His, Myc) is the recombinant human-derived INSIG2 protein, expressed by E. coli Cell-free , with N-10*His, C-Myc labeled tag. The total length of INSIG2 Protein, Human (Cell-Free, His, Myc) is 225 a.a., with molecular weight of 32.2 kDa.
  • HY-P73906

    insulin-like growth factor II; IGF-II; Preptin; IGF2; PP1446

    Human P. pastoris
    The IGF2 protein is an important member of the insulin-like growth factor family and plays an important role in mammalian growth, fetoplacental development, and adult glucose metabolism. Regulated by placental prolactin, affecting tissue differentiation. IGF2 Protein, Human (P.pastoris) is the recombinant human-derived IGF2 protein, expressed by P. pastoris , with tag free. The total length of IGF2 Protein, Human (P.pastoris) is 67 a.a., with molecular weight of ~7.5 kDa.
  • HY-P76410

    insulin-like growth factor-binding protein 5; IGFBP5

    Canine HEK293
    IGFBP-5 is only one of a family of six IGFBPs. IGFBP-5 is a 29 kDa phosphorylated and glycosylated protein, which is secreted by a wide variety of cell types during different growth conditions. IGFBP-5, the most conserved IGFBP, is the major protein secreted by skeletal muscles. IGFBP-5 Protein, Canine (HEK293, Fc) is the recombinant canine-derived IGFBP-5 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IGFBP-5 Protein, Canine (HEK293, Fc) is 252 a.a., with molecular weight of ~40 & 43 & 45 & 65 KDa, respectively.
  • HY-P77395

    insulin growth factor-like family member 2; IGFL2

    Human HEK293
    The IGFL2 protein emerged as a potential ligand for the IGFLR1 cell membrane receptor, suggesting a role in mediating cell signaling events. As a putative ligand, IGFL2 is primed to interact with the IGFLR1 receptor, suggesting involvement in cellular responses and signaling cascades. IGFL2 Protein, Human (HEK293, Fc) is the recombinant human-derived IGFL2 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of IGFL2 Protein, Human (HEK293, Fc) is 94 a.a., with molecular weight of ~38.9 KDa.
  • HY-P72256

    CD221; CD221 antigen ; IGF 1 receptor; IGF 1R; IGF I receptor; IGF-I receptor; Igf1r; IGF1R_HUMAN; IGFIR; IGFIRC; IGFR; insulin like growth factor 1 receptor; insulin like growth factor 1 receptor precursor; insulin-like growth factor 1 receptor beta chain; insulin-like growth factor I receptor; JTK13; MGC142170; MGC142172; MGC18216; Soluble IGF1R variant 1; Soluble IGF1R variant 2

    Human E. coli
    IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (His) is the recombinant human-derived IGF-I R protein, expressed by E. coli , with N-6*His labeled tag. The total length of IGF-I R Protein, Human (His) is 169 a.a., with molecular weight of ~27 kDa.
  • HY-P74848

    insulin-like growth factor-binding protein 1; IGFBP1

    Rhesus Macaque HEK293
    IGFBP-1 Protein, a member of the insulin-like growth factor-binding protein (IGFBP) family, extends IGFs' half-life and modulates their growth-promoting effects on cell culture, inhibiting or stimulating these responses. Crucially, it alters the interaction between IGFs and their cell surface receptors and promotes cell migration. Notably versatile, IGFBP-1 shows equal binding affinity for both IGF1 and IGF2, underscoring its diverse role in modulating the biological activities of insulin-like growth factors. IGFBP-1 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived IGFBP-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGFBP-1 Protein, Rhesus Macaque (HEK293, His) is 234 a.a., with molecular weight of ~30 kDa.
  • HY-P700241AF

    insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1

    Pig E. coli
    The IGF-I protein is structurally similar to insulin and has excellent growth-promoting activity. As a potential physiological regulator, it affects [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Animal-Free IGF-I Protein, Pig (His) is the recombinant pig-derived animal-FreeIGF-I protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IGF-I Protein, Pig (His) is 70 a.a., with molecular weight of ~8.59 kDa.
  • HY-P77395A

    insulin growth factor-like family member 2; IGFL2

    Human HEK293
  • HY-P74843

    insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1

    Mouse P. pastoris
    IGF-I/IGF-1 Protein, part of the insulin family, is highlighted. IGF-I/IGF-1 Protein, Mouse (P.pastoris) is the recombinant mouse-derived IGF-I/IGF-1 protein, expressed by P. pastoris, with tag free. The total length of IGF-I/IGF-1 Protein, Mouse (P.pastoris) is 70 a.a., with molecular weight of ~7.7 kDa.
  • HY-P74849

    insulin-like growth factor-binding protein 1; PP12; IBP-1

    Canine HEK293
    IGFBP-1 Protein is a member of the insulin-like growth factor binding protein (IGFBP) family that binds insulin-like growth factor (IGFs) I and II to extend the half-life of IGFs. IGFBP-1 inhibits proliferation, invasion, migration and apoptosis of HTR-8/SVneo cells by inducing MMP-26 expression. IGFBP1 may be a new prognostic factor and a target of molecular targeted therapy for gastric cancer. IGFBP-1 Protein, Canine (HEK293, His) is the recombinant canine-derived IGFBP-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGFBP-1 Protein, Canine (HEK293, His) is 224 a.a., with molecular weight of ~27 kDa.
  • HY-P73136

    insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1

    Human HEK293
    The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (HEK293, hFc) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of IGF-I/IGF-1 Protein, Human (HEK293, hFc) is 70 a.a., with molecular weight of 35-40 kDa.
  • HY-P73140

    insulin-like growth factor-binding protein 5; IBP-5; IGFBP-5; IBP5

    Human Sf9 insect cells
    The IGFBP-5 protein regulates insulin-like growth factor (IGF) and extends its lifespan. It can inhibit or stimulate the growth-promoting effect of IGF, showing its dual regulatory function. IGFBP-5 Protein, Human (sf9, His) is the recombinant human-derived IGFBP-5 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of IGFBP-5 Protein, Human (sf9, His) is 252 a.a., with molecular weight of ~30 kDa.
  • HY-P73141

    insulin-like growth factor-binding protein 6; IBP-6; IGFBP-6; IBP6

    Human HEK293
    IGFBP-6 protein is an important IGFBP member that regulates insulin-like growth factor (IGF) by changing its interaction with cell surface receptors, thereby affecting IGF-induced growth responses. In addition to regulating IGF signaling, IGFBP-6 also activates the MAPK pathway and induces cell migration. IGFBP-6 Protein, Human (HEK293, His) is the recombinant human-derived IGFBP-6 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGFBP-6 Protein, Human (HEK293, His) is 240 a.a., with molecular weight of ~36 kDa.
  • HY-P73142

    insulin-like growth factor-binding protein 7; IGFBP7; TAF; MAC25; PSF

    Human HEK293
    IGFBP-7 Protein, with relatively low IGF-I and IGF-II affinity, stimulates prostacyclin (PGI2) production and enhances cell adhesion. The significance of its interaction with VPS24/CHMP3 remains uncertain and warrants further investigation. IGFBP-7 Protein, Human (HEK293, Fc) is the recombinant human-derived IGFBP-7 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IGFBP-7 Protein, Human (HEK293, Fc) is 256 a.a., with molecular weight of 60-70 kDa.
  • HY-P73905

    insulin-like growth factor-binding protein 6; IBP-6; IGFBP-6; IBP6

    Rat HEK293
    IGFBP-6 protein modulates IGFs' activity, extending their half-life and exhibiting dual regulatory capacity. It activates the MAPK pathway, induces cell migration, and interacts with PHB2. These diverse functions emphasize IGFBP-6's multifaceted role in cellular responses related to growth regulation, signaling, and migration. IGFBP-6 Protein, Rat (HEK293, His) is the recombinant rat-derived IGFBP-6 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGFBP-6 Protein, Rat (HEK293, His) is 201 a.a., with molecular weight of 25-30 kDa.
  • HY-P77394

    insulin-like growth factor-binding protein 5; IBP-5; IGFBP-5; IBP5

    Cynomolgus HEK293
    IGFBP-5 protein modulates IGFs, extending their life span and regulating their growth effects. It inhibits or stimulates IGFs, showing its dual function. By altering IGFs' interaction with cell receptors, IGFBP-5 fine-tunes growth-associated signaling pathways, governing cellular responses. This interplay reveals IGFBP-5's multifaceted role in cellular growth and proliferation. IGFBP-5 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IGFBP-5 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGFBP-5 Protein, Cynomolgus (HEK293, His) is 252 a.a., with molecular weight of ~35 kDa.
  • HY-P73138

    insulin-like growth factor-binding protein 3; IGF-BP3; IBP-3; IGFBP-3

    Human HEK293
    IGFBP-3 protein is a part of IGFBP that significantly prolongs IGF half-life and modulates growth effects in cell culture. It inhibits or stimulates IGF-induced cellular responses by changing the kinetics of interaction with cell surface receptors. IGFBP-3 Protein, Human (HEK293, His) is the recombinant human-derived IGFBP-3 protein, expressed by HEK293 , with N-His labeled tag. The total length of IGFBP-3 Protein, Human (HEK293, His) is 264 a.a., with molecular weight of 40-45 kDa.
  • HY-P74844

    IBP-7; IGFBP7; IGFBP-7v; insulin-like growth factor binding protein 7

    Mouse HEK293
    IGFBP-7 Protein is a member of the insulin-like growth factor binding protein (IGFBP) Family. The major function of IGFBP-7 is the regulation of availability of insulin-like growth factors (IGFs) in tissue as well as in modulating IGF binding to its receptors. IGFBP7 exhibits a relatively low affinity for binding to both IGF-I and IGF-II. Furthermore, it has the capacity to stimulate the production of prostacyclin (PGI2) and enhance cell adhesion. IGFBP-7 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IGFBP-7 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IGFBP-7 Protein, Mouse (HEK293, Fc) is 256 a.a., with molecular weight of ~53.3-60 kDa.
  • HY-P74845

    BP-4; HT29-IGFBP; IBP4; insulin-like growth factor-binding protein 4

    Mouse HEK293
    IGFBP-4 protein modulates IGFs' activity and can either inhibit or stimulate their growth-promoting effects. It alters the interaction between IGFs and their receptors, with a preference for binding to IGF2. This highlights the nuanced role of IGFBP-4 in fine-tuning IGF-mediated cellular responses. IGFBP-4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-4 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGFBP-4 Protein, Mouse (HEK293, His) is 254 a.a., with molecular weight of ~38 kDa.
  • HY-P74846

    IBP-2; insulin-like growth factor binding protein 2; IGFBP2; IGF-BP53

    Mouse HEK293
    IGFBP-2 protein, a member of the IGF-binding protein family, inhibits IGF-mediated growth and developmental rates. It can extend the half-life of IGF and exhibit dual functions by inhibiting or stimulating the growth-promoting effect of IGF in cell culture. IGFBP-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-2 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGFBP-2 Protein, Mouse (HEK293, His) is 271 a.a., with molecular weight of ~32-40 kDa.
  • HY-P74847

    IBP-2; insulin-like growth factor binding protein 2; IGFBP2; IGF-BP53

    Mouse HEK293
    IGFBP-2 protein, a member of the IGF-binding protein family, inhibits IGF-mediated growth and developmental rates. It can extend the half-life of IGF and exhibit dual functions by inhibiting or stimulating the growth-promoting effect of IGF in cell culture. IGFBP-2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IGFBP-2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IGFBP-2 Protein, Mouse (HEK293, Fc) is 305 a.a., with molecular weight of ~56.6 kDa.
  • HY-P72606

    insulin-like growth factor 1 receptor; IGF-I receptor; IGF1R; CD221

    Human HEK293
    IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (HEK293, His) is the recombinant human-derived IGF-I R protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IGF-I R Protein, Human (HEK293, His) is 902 a.a., with molecular weight of 100-130 & 54 kDa, respectively.
  • HY-P70357

    rMuinsulin-like growth factor-binding protein 6/IGFBP-6, His; insulin-like growth factor-binding protein 6; IBP-6; IGF-binding protein 6; IGFBP-6; Igfbp6; IBP6; IGF binding protein 6; insulin-like growth factor-binding protein 6

    Mouse HEK293
    IGFBP-6 protein can extend the half-life of IGF and regulate its effects. It can inhibit or stimulate the growth-promoting effects of IGF. IGFBP-6 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-6 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IGFBP-6 Protein, Mouse (HEK293, His) is 213 a.a., with molecular weight of ~28.0 kDa.
  • HY-P73137

    insulin-like growth factor 1 receptor; IGF-I receptor; CD221; IGF1R

    Human Sf9 insect cells
    IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (sf9, His-GST) is the recombinant human-derived IGF-I R protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of IGF-I R Protein, Human (sf9, His-GST) is 414 a.a., with molecular weight of ~74.6 kDa.
  • HY-P74442

    insulin-like growth factor 1 receptor; IGF-I receptor; CD221; IGF1R

    Human HEK293
    IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (HEK293, His, solution) is the recombinant human-derived IGF-I R protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P77393

    insulin-like growth factor-binding protein 4; IGF-BP-4; IBP-4; IGFBP-4; BP4

    Cynomolgus HEK293
    IGFBP-4 protein lacks essential conserved residue(s) for propagating feature annotation. IGFBP-4 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IGFBP-4 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGFBP-4 Protein, Cynomolgus (HEK293, His) is 235 a.a., with molecular weight of 33-36 kDa.
  • HY-P70787

    insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1

    Human E. coli
    The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (67a.a) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by E. coli , with tag free. The total length of IGF-I/IGF-1 Protein, Human (67a.a) is 67 a.a., with molecular weight of ~9.0 kDa.
  • HY-P70788
    IGF-I/IGF-1 Protein, Human (G49-A118)
    5 Publications Verification

    insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1

    Human E. coli
    The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (G49-A118) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by E. coli , with tag free. The total length of IGF-I/IGF-1 Protein, Human (G49-A118) is 70 a.a., with molecular weight of ~9.0 kDa.
  • HY-P700256

    insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1; PP12

    Mouse E. coli
    The IGFBP-1 protein is an insulin-like growth factor binding protein that extends the half-life of IGF and modulates its growth-promoting effects in cell cultures, thereby inhibiting or stimulating these responses. Crucially, it alters the interaction between IGF and its cell surface receptors and promotes cell migration. IGFBP-1 Protein, Mouse (SUMO, His) is the recombinant mouse-derived IGFBP-1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of IGFBP-1 Protein, Mouse (SUMO, His) is 247 a.a., with molecular weight of ~43 kDa.
  • HY-P700478

    insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1

    Human P. pastoris
    The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (P. pastoris, N-His) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of IGF-I/IGF-1 Protein, Human (P. pastoris, N-His) is 70 a.a., with molecular weight of 9.7 kDa.
  • HY-P72608

    insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1; PP12

    Human HEK293
    IGFBP-1 protein extends the half-life of IGFs and modulates their activity. It can inhibit or stimulate IGFs' growth-promoting effects, altering their interaction with receptors and fine-tuning signaling pathways. IGFBP-1 promotes cell migration and binds to both IGF1 and IGF2, highlighting its versatile role in modulating IGF signaling pathways. IGFBP-1 Protein, Human (HEK293, His) is the recombinant human-derived IGFBP-1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IGFBP-1 Protein, Human (HEK293, His) is 234 a.a., with molecular weight of 30-35 kDa.
  • HY-P70783

    Long R3 IGF-I; insulin-like growth factor I; MGF; Somatomedin-C; IBP1

    Human E. coli
    The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) is the recombinant human-derived LR3 IGF-I/IGF-1 protein, expressed by E. coli , with tag free. and E51R, , , , mutation. The total length of LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) is 70 a.a., with molecular weight of ~11.0 kDa.
  • HY-P76409

    insulin-like growth factor 2 mRNA-binding protein 2; IMP-2; IGF2BP2; VICKZ2

    Rhesus Macaque HEK293
    IGFBP‐2 is a member of a family of six insulin‐like growth factor (IGF) binding proteins. IGFBP-2 is the second most abundant IGFBP in the circulation and binds IGF-II with higher affinity than IGF-I. IGFBP-2 has been implicated in the regulation of IGF activity in most tissues and organs. IGFBP-2 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived IGFBP-2 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P70783G

    Long R3 IGF-I; insulin-like growth factor I; MGF; Somatomedin-C; IBP1

    Human E. coli
    The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. GMP LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) is the recombinant human-derived LR3 IGF-I/IGF-1 protein, expressed by E. coli , with tag free. The total length of GMP LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) is 70 a.a., with molecular weight of ~11 kDa.