1. Natural Products
  2. Quinones

Quinones

The quinones represent a class of organic compounds that are formally "derived from aromatic compounds [such as benzene or naphthalene] by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds", resulting in "a fully conjugated cyclic dione structure". The class includes some heterocyclic compounds. A large scale industrial application of quinones is for the production of hydrogen peroxide. Natural quinones show a biological or pharmacological activity, and some of them show anti-tumoral activity. They embody some claims in herbal medicine. Some quinone derivatives are used for coloring substances (dyes and pigments) and oxidizing agents.

Quinones (73):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-13062
    Daunorubicin Hydrochloride 23541-50-6 99.37%
    Daunorubicin Hydrochloride (Daunomycin Hydrochloride; RP 13057 Hydrochloride; Rubidomycin Hydrochloride) is a topoisomerase II inhibitor with potent antineoplastic activities. Daunorubicin Hydrochloride (Daunomycin Hydrochloride; RP 13057 Hydrochloride; Rubidomycin Hydrochloride) inhibites DNA and RNA synthesis in sensitive and resistant Ehrlich ascites tumor cells.
    Daunorubicin Hydrochloride
  • HY-N0822
    Shikonin 517-89-5 99.80%
    Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC50 of 6.5 μM. Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor and can also inhibit TNF-α and NF-κB pathway.
    Shikonin
  • HY-N0174
    Cryptotanshinone 35825-57-1 98.17%
    Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC50 of 4.6 μM.
    Cryptotanshinone
  • HY-13555
    β-Lapachone 4707-32-8 99.98%
    β-Lapachone (ARQ-501;NSC-26326) is a naturally occurring O-naphthoquinone, acts as a topoisomerase I inhibitor, and induces apoptosis by inhibiting cell cycle progression.
    β-Lapachone
  • HY-14393
    Emodin 518-82-1 >98.0%
    Emodin is a broad-spectrum anticancer agent. Emodin inhibits casein kinase II (CKII) activity with IC50 of 2 μM.
    Emodin
  • HY-N0111
    Coenzyme Q10 303-98-0 >98.0%
    Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
    Coenzyme Q10
  • HY-N0105
    Rhein 478-43-3 >99.0%
    Rhein is a lipophilic anthraquinone extensively found in medicinal herbs, and has many pharmacological effects, including epatoprotective, nephroprotective, anti-inflammatory, antioxidant, anticancer, and antimicrobial activities.
    Rhein
  • HY-N0142
    Phloretin 60-82-2 99.70%
    Phloretin (NSC 407292; RJC 02792) is a flavonoid extracted from Prunus mandshurica, has anti-inflammatory activities. Phloridzin is a specific, competitive and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2). Phloretin inhibits Yeast-made GLUT1 as well as Human erythrocyte GLUT1 with IC50values of 49 μM and 61 μM, respectively.Phloretin has the potential for the treatment of rheumatoid arthritis (RA) and allergic airway inflammation.
    Phloretin
  • HY-N0135
    Tanshinone IIA 568-72-9 99.07%
    Tanshinone IIA (Tan IIA) is one of the main fat-soluble compositions in the root of red-rooted salvia. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.
    Tanshinone IIA
  • HY-N0684
    Vitamin K1 84-80-0 >98.0%
    Vitamin K1 a fat-soluble, naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
    Vitamin K1
  • HY-B0923
    Danthron 117-10-2 >98.0%
    Danthron is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron functions in regulating glucose and lipid metabolism by activating AMPK.
    Danthron
  • HY-N0283
    Diacerein 13739-02-1 98.78%
    Diacerein (Diacerhein), a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases.
    Diacerein
  • HY-N0360
    Dihydrotanshinone I 87205-99-0 99.59%
    Dihydrotanshinone I is a natural compound extracted from Salvia miltiorrhiza Bunge which has been widely used for treating cardiovascular diseases.
    Dihydrotanshinone I
  • HY-B0332
    Menadione 58-27-5 98.57%
    Menadione, a synthetic naphthoquinone, can be converted to active vitamin K2 in vivo.
    Menadione
  • HY-N1370
    Tanshinone IIA sulfonate sodium 69659-80-9 >98.0%
    Tanshinone IIA sulfonate (sodium) is a derivative of tanshinone IIA, which acts as an inhibitor of store-operated Ca2+ entry (SOCE), and is used to treat cardiovascular disorders.
    Tanshinone IIA sulfonate sodium
  • HY-100875
    Bisantrene 78186-34-2
    Bisantrene is a highly effective antitumor drug, targets eukaryotic type II topoisomerases.
    Bisantrene
  • HY-N0134
    Tanshinone I 568-73-0 >98.0%
    Tanshinone I is an inhibitor of type IIA human recombinant sPLA2 (IC50=11 μM) and rabbit recombinant cPLA2 (IC50=82 μM).
    Tanshinone I
  • HY-101415
    Coenzyme Q9 303-97-9 >98.0%
    Coenzyme Q9, a nine isoprenyl group-containing member of the ubiquinone family, is a normal constituent of human plasma.
    Coenzyme Q9
  • HY-B1919
    Dihydroisotanshinone I 20958-18-3 99.61%
    Dihydroisotanshinone I is a bioactive compound present in a widely used traditional Chinese medicine named danshen.
    Dihydroisotanshinone I
  • HY-17473
    Embelin 550-24-3 98.75%
    Embelin is a cell-permeable benzoquinone compound that exhibits antitumor properties.
    Embelin