1. Natural Products
  2. Quinones

Quinones

The quinones represent a class of organic compounds that are formally "derived from aromatic compounds [such as benzene or naphthalene] by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds", resulting in "a fully conjugated cyclic dione structure". The class includes some heterocyclic compounds. A large scale industrial application of quinones is for the production of hydrogen peroxide. Natural quinones show a biological or pharmacological activity, and some of them show anti-tumoral activity. They embody some claims in herbal medicine. Some quinone derivatives are used for coloring substances (dyes and pigments) and oxidizing agents.

Quinones (59):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0822
    Shikonin 517-89-5 99.80%
    Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC50 of 6.5 μM. Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor and can also inhibit TNF-α and NF-κB pathway.
    Shikonin
  • HY-13062
    Daunorubicin Hydrochloride 23541-50-6 99.37%
    Daunorubicin Hydrochloride (Daunomycin Hydrochloride; RP 13057 Hydrochloride; Rubidomycin Hydrochloride) is a topoisomerase II inhibitor with potent antineoplastic activities. Daunorubicin Hydrochloride (Daunomycin Hydrochloride; RP 13057 Hydrochloride; Rubidomycin Hydrochloride) inhibites DNA and RNA synthesis in sensitive and resistant Ehrlich ascites tumor cells.
    Daunorubicin Hydrochloride
  • HY-N0174
    Cryptotanshinone 35825-57-1 98.17%
    Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC50 of 4.6 μM.
    Cryptotanshinone
  • HY-13555
    β-Lapachone 4707-32-8 99.98%
    β-Lapachone is a naturally occurring O-naphthoquinone, acts as a topoisomerase I inhibitor, and induces apoptosis by inhibiting cell cycle progression.
    β-Lapachone
  • HY-14393
    Emodin 518-82-1 >98.0%
    Emodin is a broad-spectrum anticancer agent. Emodin inhibits casein kinase II (CKII) activity with IC50 of 2 μM.
    Emodin
  • HY-N0105
    Rhein 478-43-3 >99.0%
    Rhein is a lipophilic anthraquinone extensively found in medicinal herbs, and has many pharmacological effects, including epatoprotective, nephroprotective, anti-inflammatory, antioxidant, anticancer, and antimicrobial activities.
    Rhein
  • HY-N0142
    Phloretin 60-82-2 99.70%
    Phloretin(NSC 407292; RJC 02792) is a dihydrochalcone, a type of natural phenols. Phloretin inhibits the active transport of glucose into cells by SGLT1 and SGLT2.
    Phloretin
  • HY-N0684
    Vitamin K1 84-80-0 >98.0%
    Vitamin K1 a fat-soluble, naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
    Vitamin K1
  • HY-N0283
    Diacerein 13739-02-1 98.78%
    Diacerein (Diacerhein), a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases.
    Diacerein
  • HY-N1370
    Tanshinone IIA sulfonate sodium 69659-80-9 >98.0%
    Tanshinone IIA sulfonate (sodium) is a water-soluble derivative of tanshinone IIA, which acts as an inhibitor of store-operated Ca2+ entry (SOCE), and is used to treat cardiovascular disorders.
    Tanshinone IIA sulfonate sodium
  • HY-N0111
    Coenzyme Q10 303-98-0 >98.0%
    Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
    Coenzyme Q10
  • HY-B0332
    Menadione 58-27-5 98.57%
    Menadione, a synthetic naphthoquinone, can be converted to active vitamin K2 in vivo.
    Menadione
  • HY-B0923
    Danthron 117-10-2 >98.0%
    Danthron is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron functions in regulating glucose and lipid metabolism by activating AMPK.
    Danthron
  • HY-N0135
    Tanshinone IIA 568-72-9 99.07%
    Tanshinone IIA (Tan IIA) is one of the main fat-soluble compositions in the root of red-rooted salvia. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.
    Tanshinone IIA
  • HY-101415
    Coenzyme Q9 303-97-9 >98.0%
    Coenzyme Q9, a nine isoprenyl group-containing member of the ubiquinone family, is a normal constituent of human plasma.
    Coenzyme Q9
  • HY-17473
    Embelin 550-24-3 98.75%
    Embelin is a cell-permeable benzoquinone compound that exhibits antitumor properties.
    Embelin
  • HY-N0360
    Dihydrotanshinone I 87205-99-0 99.59%
    Dihydrotanshinone I is a natural compound extracted from Salvia miltiorrhiza Bunge which has been widely used for treating cardiovascular diseases.
    Dihydrotanshinone I
  • HY-100875
    Bisantrene 78186-34-2
    Bisantrene is a highly effective antitumor drug, targets eukaryotic type II topoisomerases.
    Bisantrene
  • HY-N0123
    Aloin 1415-73-2 98.78%
    Aloin(Aloin-A; Barbaloin-A) is a natural antitumor anthraquinone glycoside with iron chelating and non-atherogenic activities.
    Aloin
  • HY-N0303
    Idebenone 58186-27-9 99.62%
    Idebenone is a synthetic variant of coenzyme Q10 (CoQ10), which initially developed for the treatment of Alzheimer's disease and other cognitive defects.
    Idebenone